Mammalian models of extended healthy lifespan

por Selman, Colin, Withers, Dominic J.
Publicado 2011

Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1

por Selman, Colin, Partridge, Linda, Withers, Dominic J.
Publicado 2011

Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat

por Li, Xinzhong, Thomason, Peter A, Withers, Dominic J, Scott, James
Publicado 2010

Genomic imprinting and its effects on postnatal growth and adult metabolism

por Millership, Steven J., Van de Pette, Mathew, Withers, Dominic J.
Publicado 2019

Metabotyping of Long-Lived Mice using (1)H NMR Spectroscopy

por Wijeyesekera, Anisha, Selman, Colin, Barton, Richard H., Holmes, Elaine, Nicholson, Jeremy K., Withers, Dominic J.
Publicado 2012

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

por Page, Melissa M., Schuster, Eugene F., Mudaliar, Manikhandan, Herzyk, Pawel, Withers, Dominic J., Selman, Colin
Publicado 2018

Reduced insulin signaling in neurons induces sex-specific health benefits

por Baghdadi, Maarouf, Nespital, Tobias, Mesaros, Andrea, Buschbaum, Sandra, Withers, Dominic J., Grönke, Sebastian, Partridge, Linda
Publicado 2023

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

por Page, Melissa M, Sinclair, Amy, Robb, Ellen L, Stuart, Jeffrey A, Withers, Dominic J, Selman, Colin
Publicado 2014

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

por Jové, Mariona, Naudí, Alba, Ramírez-Núñez, Omar, Portero-Otín, Manuel, Selman, Colin, Withers, Dominic J, Pamplona, Reinald
Publicado 2014

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

por Selman, Colin, Sinclair, Amy, Pedroni, Silvia M.A., Irvine, Elaine E., Michie, Alison M., Withers, Dominic J.
Publicado 2016

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

por Foukas, Lazaros C, Bilanges, Benoit, Bettedi, Lucia, Pearce, Wayne, Ali, Khaled, Sancho, Sara, Withers, Dominic J, Vanhaesebroeck, Bart
Publicado 2013

Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease

por Irvine, Elaine E., Katsouri, Loukia, Plattner, Florian, Al-Qassab, Hind, Al-Nackkash, Rand, Bates, Gillian P., Withers, Dominic J.
Publicado 2019

Calcium Channel Ca(V)2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons

por Smith, Mark A., Katsouri, Loukia, Virtue, Samuel, Choudhury, Agharul I., Vidal-Puig, Antonio, Ashford, Michael L.J., Withers, Dominic J.
Publicado 2018

Galactose‐modified duocarmycin prodrugs as senolytics

por Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús
Publicado 2020

PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice

por Deas, Emma, Piipari, Kaisa, Machhada, Asif, Li, Abi, Gutierrez-del-Arroyo, Ana, Withers, Dominic J., Wood, Nicholas W., Abramov, Andrey Y.
Publicado 2014

Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk

por Slack, Cathy, Werz, Christian, Wieser, Daniela, Alic, Nazif, Foley, Andrea, Stocker, Hugo, Withers, Dominic J., Thornton, Janet M., Hafen, Ernst, Partridge, Linda
Publicado 2010

Loss of AMP-activated protein kinase α2 subunit in mouse β-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

por Beall, Craig, Piipari, Kaisa, Al-Qassab, Hind, Smith, Mark A., Parker, Nadeene, Carling, David, Viollet, Benoit, Withers, Dominic J., Ashford, Michael L. J.
Publicado 2010

nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta

por Paul, Eleanor J., Kalk, Eliza, Tossell, Kyoko, Irvine, Elaine E., Franks, Nicholas P., Wisden, William, Withers, Dominic J., Leiper, James, Ungless, Mark A.
Publicado 2018

RF13 | PMON143 BRF1-Mediated Paracrine Signalling by a Subset of SOX2-Expressing Stem Cells is Required for Normal Development of the Stem Cell Compartment and Terminal Differentia...

por Manshaei, Saba, Willis, Thea L, Reen, Virinder, Pallikonda, Husayn, Birch, Jodie, Withers, Dominic J, Gil, Jesus, Andoniadou, Cynthia L, Martinez-Barbera, Juan Pedro
Publicado 2022

Diet and Gastrointestinal Bypass–Induced Weight Loss: The Roles of Ghrelin and Peptide YY

por Chandarana, Keval, Gelegen, Cigdem, Karra, Efthimia, Choudhury, Agharul I., Drew, Megan E., Fauveau, Veronique, Viollet, Benoit, Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Publicado 2011