Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract

por Bernacki, Derek T., Bryce, Steven M., Bemis, Jeffrey C., Dertinger, Stephen D., Witt, Kristine L., Smith‐Roe, Stephanie L.
Publicado 2019

Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays

por Lynch, Caitlin, Zhao, Jinghua, Sakamuru, Srilatha, Zhang, Li, Huang, Ruili, Witt, Kristine L., Merrick, B. Alex, Teng, Christina T., Xia, Menghang
Publicado 2019

Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

por Attene-Ramos, Matias S., Huang, Ruili, Michael, Sam, Witt, Kristine L., Richard, Ann, Tice, Raymond R., Simeonov, Anton, Austin, Christopher P., Xia, Menghang
Publicado 2014

Next generation high throughput DNA damage detection platform for genotoxic compound screening

por Sykora, Peter, Witt, Kristine L., Revanna, Pooja, Smith-Roe, Stephanie L., Dismukes, Jonathan, Lloyd, Donald G., Engelward, Bevin P., Sobol, Robert W.
Publicado 2018

Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

por Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
Publicado 2012

Interaction between DNA Polymerase β and BRCA1

por Masaoka, Aya, Gassman, Natalie R., Horton, Julie K., Kedar, Padmini S., Witt, Kristine L., Hobbs, Cheryl A., Kissling, Grace E., Tano, Keizo, Asagoshi, Kenjiro, Wilson, Samuel H.
Publicado 2013

Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

por Ooka, Masato, Zhao, Jinghua, Shah, Pranav, Travers, Jameson, Klumpp-Thomas, Carleen, Xu, Xin, Huang, Ruili, Ferguson, Stephen, Witt, Kristine L., Smith-Roe, Stephanie L., Simeonov, Anton, Xia, Menghang
Publicado 2022

Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening

por Xia, Menghang, Huang, Ruili, Witt, Kristine L., Southall, Noel, Fostel, Jennifer, Cho, Ming-Hsuang, Jadhav, Ajit, Smith, Cynthia S., Inglese, James, Portier, Christopher J., Tice, Raymond R., Austin, Christopher P.
Publicado 2008

Hexavalent Chromium Is Carcinogenic to F344/N Rats and B6C3F1 Mice after Chronic Oral Exposure

por Stout, Matthew D., Herbert, Ronald A., Kissling, Grace E., Collins, Bradley J., Travlos, Gregory S., Witt, Kristine L., Melnick, Ronald L., Abdo, Kamal M., Malarkey, David E., Hooth, Michelle J.
Publicado 2009

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

por Huang, Ruili, Xia, Menghang, Cho, Ming-Hsuang, Sakamuru, Srilatha, Shinn, Paul, Houck, Keith A., Dix, David J., Judson, Richard S., Witt, Kristine L., Kavlock, Robert J., Tice, Raymond R., Austin, Christopher P.
Publicado 2011

Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure

por Smith‐Roe, Stephanie L., Wyde, Michael E., Stout, Matthew D., Winters, John W., Hobbs, Cheryl A., Shepard, Kim G., Green, Amanda S., Kissling, Grace E., Shockley, Keith R., Tice, Raymond R., Bucher, John R., Witt, Kristine L.
Publicado 2019

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity

por French, John E., Gatti, Daniel M., Morgan, Daniel L., Kissling, Grace E., Shockley, Keith R., Knudsen, Gabriel A., Shepard, Kim G., Price, Herman C., King, Deborah, Witt, Kristine L., Pedersen, Lars C., Munger, Steven C., Svenson, Karen L., Churchill, Gary A.
Publicado 2014

Erratum: “Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity”

por French, John E., Gatti, Daniel M., Morgan, Daniel L., Kissling, Grace E., Shockley, Keith R., Knudsen, Gabriel A., Shepard, Kim G., Price, Herman C., King, Deborah, Witt, Kristine L., Pedersen, Lars C., Munger, Steven C., Svenson, Karen L., Churchill, Gary A.
Publicado 2018

A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements

por Smith‐Roe, Stephanie L., Garantziotis, Stavros, Church, Rebecca L., Bemis, Jeffrey C., Torous, Dorothea K., Shepard, Kim G., Hobbs, Cheryl A., Waidyanatha, Suramya, Mutlu, Esra, Shockley, Keith R., Kissling, Grace E., McBride, Sandra J., Xie, Guanhua, Cristy, Tim, Pierfelice, Jessica, Witt, Kristine L.
Publicado 2022

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

por Huang, Ruili, Sakamuru, Srilatha, Martin, Matt T., Reif, David M., Judson, Richard S., Houck, Keith A., Casey, Warren, Hsieh, Jui-Hua, Shockley, Keith R., Ceger, Patricia, Fostel, Jennifer, Witt, Kristine L., Tong, Weida, Rotroff, Daniel M., Zhao, Tongan, Shinn, Paul, Simeonov, Anton, Dix, David J., Austin, Christopher P., Kavlock, Robert J., Tice, Raymond R., Xia, Menghang
Publicado 2014

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

por Xia, Menghang, Huang, Ruili, Shi, Qiang, Boyd, Windy A., Zhao, Jinghua, Sun, Nuo, Rice, Julie R., Dunlap, Paul E., Hackstadt, Amber J., Bridge, Matt F., Smith, Marjolein V., Dai, Sheng, Zheng, Wei, Chu, Pei-Hsuan, Gerhold, David, Witt, Kristine L., DeVito, Michael, Freedman, Jonathan H., Austin, Christopher P., Houck, Keith A., Thomas, Russell S., Paules, Richard S., Tice, Raymond R., Simeonov, Anton
Publicado 2018