Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches

por Wittemans, Laura B. L., Lotta, Luca A., Langenberg, Claudia
Publicado 2018

Evidence From Men for Ovary-independent Effects of Genetic Risk Factors for Polycystic Ovary Syndrome

por Zhu, Jia, Pujol-Gualdo, Natàlia, Wittemans, Laura B L, Lindgren, Cecilia M, Laisk, Triin, Hirschhorn, Joel N, Chan, Yee-Ming
Publicado 2021

The genetic architecture of changes in adiposity during adulthood

por Venkatesh, Samvida S., Ganjgahi, Habib, Palmer, Duncan S., Coley, Kayesha, Wittemans, Laura B. L., Nellaker, Christoffer, Holmes, Chris, Lindgren, Cecilia M., Nicholson, George
Publicado 2023

Obesity and risk of female reproductive conditions: A Mendelian randomisation study

por Venkatesh, Samvida S., Ferreira, Teresa, Benonisdottir, Stefania, Rahmioglu, Nilufer, Becker, Christian M., Granne, Ingrid, Zondervan, Krina T., Holmes, Michael V., Lindgren, Cecilia M., Wittemans, Laura B. L.
Publicado 2022

Correction: Obesity and risk of female reproductive conditions: A Mendelian randomisation study

por Venkatesh, Samvida S., Ferreira, Teresa, Benonisdottir, Stefania, Rahmioglu, Nilufer, Becker, Christian M., Granne, Ingrid, Zondervan, Krina T., Holmes, Michael V., Lindgren, Cecilia M., Wittemans, Laura B. L.
Publicado 2022

Regional fat depot masses are influenced by protein-coding gene variants

por Neville, Matt J., Wittemans, Laura B. L., Pinnick, Katherine E., Todorčević, Marijana, Kaksonen, Risto, Pietiläinen, Kirsi H., Luan, Jian’an, Scott, Robert A., Wareham, Nicholas J., Langenberg, Claudia, Karpe, Fredrik
Publicado 2019

Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

por Kentistou, Katherine A., Luan, Jian’an, Wittemans, Laura B. L., Hambly, Catherine, Klaric, Lucija, Kutalik, Zoltán, Speakman, John R., Wareham, Nicholas J., Kendall, Timothy J., Langenberg, Claudia, Wilson, James F., Joshi, Peter K., Morton, Nicholas M.
Publicado 2023

MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition

por Hilton, Catriona, Neville, Matt J., Wittemans, Laura B.L., Todorcevic, Marijana, Pinnick, Katherine E., Pulit, Sara L., Luan, Jian'an, Kulyté, Agné, Dahlman, Ingrid, Wareham, Nicholas J., Lotta, Luca A., Arner, Peter, Lindgren, Cecilia M., Langenberg, Claudia, Karpe, Fredrik
Publicado 2019

HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution

por Kuo, Feng-Chih, Neville, Matt J., Sabaratnam, Rugivan, Wesolowska-Andersen, Agata, Phillips, Daniel, Wittemans, Laura B.L., van Dam, Andrea D., Loh, Nellie Y., Todorčević, Marijana, Denton, Nathan, Kentistou, Katherine A., Joshi, Peter K., Christodoulides, Constantinos, Langenberg, Claudia, Collas, Philippe, Karpe, Fredrik, Pinnick, Katherine E.
Publicado 2022

Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes...

por Lotta, Luca A., Stewart, Isobel D., Sharp, Stephen J., Day, Felix R., Burgess, Stephen, Luan, Jian’an, Bowker, Nicholas, Cai, Lina, Li, Chen, Wittemans, Laura B. L., Kerrison, Nicola D., Khaw, Kay-Tee, McCarthy, Mark I., O’Rahilly, Stephen, Scott, Robert A., Savage, David B., Perry, John R. B., Langenberg, Claudia, Wareham, Nicholas J.
Publicado 2018

Assessing the causal association of glycine with risk of cardio-metabolic diseases

por Wittemans, Laura B. L., Lotta, Luca A., Oliver-Williams, Clare, Stewart, Isobel D., Surendran, Praveen, Karthikeyan, Savita, Day, Felix R., Koulman, Albert, Imamura, Fumiaki, Zeng, Lingyao, Erdmann, Jeanette, Schunkert, Heribert, Khaw, Kay-Tee, Griffin, Julian L., Forouhi, Nita G., Scott, Robert A., Wood, Angela M., Burgess, Stephen, Howson, Joanna M. M., Danesh, John, Wareham, Nicholas J., Butterworth, Adam S., Langenberg, Claudia
Publicado 2019

Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution

por Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D, Patel, Satish, Van de Streek, Marcel, Glastonbury, Craig A, Stewart, Isobel D, Day, Felix R, Luan, Jian’an, Bowker, Nicholas, Wittemans, Laura B L, Kerrison, Nicola D, Cai, Lina, Lucarelli, Debora M E, Barroso, Inês, McCarthy, Mark I, Scott, Robert A, Saudek, Vladimir, Small, Kerrin S, Wareham, Nicholas J, Semple, Robert K, Perry, John R B, O’Rahilly, Stephen, Lotta, Luca A, Langenberg, Claudia, Savage, David B
Publicado 2021

Rare and common genetic determinants of metabolic individuality and their effects on human health

por Surendran, Praveen, Stewart, Isobel D., Au Yeung, Victoria P. W., Pietzner, Maik, Raffler, Johannes, Wörheide, Maria A., Li, Chen, Smith, Rebecca F., Wittemans, Laura B. L., Bomba, Lorenzo, Menni, Cristina, Zierer, Jonas, Rossi, Niccolò, Sheridan, Patricia A., Watkins, Nicholas A., Mangino, Massimo, Hysi, Pirro G., Di Angelantonio, Emanuele, Falchi, Mario, Spector, Tim D., Soranzo, Nicole, Michelotti, Gregory A., Arlt, Wiebke, Lotta, Luca A., Denaxas, Spiros, Hemingway, Harry, Gamazon, Eric R., Howson, Joanna M. M., Wood, Angela M., Danesh, John, Wareham, Nicholas J., Kastenmüller, Gabi, Fauman, Eric B., Suhre, Karsten, Butterworth, Adam S., Langenberg, Claudia
Publicado 2022