Side effect profile similarities shared between antidepressants and immune-modulators reveal potential novel targets for treating major depressive disorders

por Sun, Yu, Narayan, Vaibhav A., Wittenberg, Gayle M.
Publicado 2016

Spike Timing Dependent Plasticity: A Consequence of More Fundamental Learning Rules

por Shouval, Harel Z., Wang, Samuel S.-H., Wittenberg, Gayle M.
Publicado 2010

Immune targets for therapeutic development in depression: towards precision medicine

por Drevets, Wayne C., Wittenberg, Gayle M., Bullmore, Edward T., Manji, Husseini K.
Publicado 2022

Application of Real-World Data and the REWARD Framework to Detect Unknown Benefits of Memantine and Identify Potential Disease Targets for New NMDA Receptor Antagonists

por Kern, David M., Cepeda, M. Soledad, Flores, Christopher M., Wittenberg, Gayle M.
Publicado 2021

Revealing Unknown Benefits of Existing Medications to Aid the Discovery of New Treatments for Post‐Traumatic Stress Disorder

por Kern, David M., Teneralli, Rachel E., Flores, Christopher M., Wittenberg, Gayle M., Gilbert, James P., Cepeda, M. Soledad
Publicado 2021

Metabolomic biosignature differentiates melancholic depressive patients from healthy controls

por Liu, Yashu, Yieh, Lynn, Yang, Tao, Drinkenburg, Wilhelmus, Peeters, Pieter, Steckler, Thomas, Narayan, Vaibhav A., Wittenberg, Gayle, Ye, Jieping
Publicado 2016

The role of anxious distress in immune dysregulation in patients with major depressive disorder

por Gaspersz, Roxanne, Lamers, Femke, Wittenberg, Gayle, Beekman, Aartjan T. F., van Hemert, Albert M., Schoevers, Robert A., Penninx, Brenda W. J. H.
Publicado 2017

Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders

por Wittenberg, Gayle M., Stylianou, Annie, Zhang, Yun, Sun, Yu, Gupta, Ashutosh, Jagannatha, P. S., Wang, Dai, Hsu, Benjamin, Curran, Mark E., Khan, Shahid, Chen, Guang, Bullmore, Edward T., Drevets, Wayne C.
Publicado 2019

Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder

por Leday, Gwenaël G.R., Vértes, Petra E., Richardson, Sylvia, Greene, Jonathan R., Regan, Tim, Khan, Shahid, Henderson, Robbie, Freeman, Tom C., Pariante, Carmine M., Harrison, Neil A., Perry, V. Hugh, Drevets, Wayne C., Wittenberg, Gayle M., Bullmore, Edward T.
Publicado 2018

Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

por Leung, Yuk Yee, Toledo, Jon B., Nefedov, Alexey, Polikar, Robi, Raghavan, Nandini, Xie, Sharon X., Farnum, Michael, Schultz, Tim, Baek, Young, Van Deerlin, Vivianna M., Hu, William T., Holtzman, David M., Fagan, Anne M., Perrin, Richard J., Grossman, Murray, Soares, Holly D., Kling, Mitchel A., Mailman, Matthew, Arnold, Steven E., Narayan, Vaibhav A., Lee, Virginia M-Y., Shaw, Leslie M., Baker, David, Wittenberg, Gayle M., Trojanowski, John Q., Wang, Li-San
Publicado 2015

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

por Lopez, Juan Pablo, Fiori, Laura M., Cruceanu, Cristiana, Lin, Rixing, Labonte, Benoit, Cates, Hannah M., Heller, Elizabeth A., Vialou, Vincent, Ku, Stacy M., Gerald, Christophe, Han, Ming-Hu, Foster, Jane, Frey, Benicio N., Soares, Claudio N., Müller, Daniel J., Farzan, Faranak, Leri, Francesco, MacQueen, Glenda M., Feilotter, Harriet, Tyryshkin, Kathrin, Evans, Kenneth R., Giacobbe, Peter, Blier, Pierre, Lam, Raymond W., Milev, Roumen, Parikh, Sagar V., Rotzinger, Susan, Strother, Steven C., Lewis, Cathryn M., Aitchison, Katherine J., Wittenberg, Gayle M., Mechawar, Naguib, Nestler, Eric J., Uher, Rudolf, Kennedy, Sidney H., Turecki, Gustavo
Publicado 2017