Amphetamine-Like Analogues in Diabetes: Speeding towards Ketogenesis

por Branis, Natalia M., Wittlin, Steven D.
Publicado 2015

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains

por Abiodun, Oyindamola O, Brun, Reto, Wittlin, Sergio
Publicado 2013

A new double-antibody sandwich ELISA targeting Plasmodium falciparum aldolase to evaluate anti-malarial drug sensitivity

por Tritten, Lucienne, Matile, Hugues, Brun, Reto, Wittlin, Sergio
Publicado 2009

Two successful decades of Swiss collaborations to develop new anti-malarials

por Hooft van Huijsduijnen, Rob, Wells, Timothy, Tanner, Marcel, Wittlin, Sergio
Publicado 2019

Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay

por Walz, Annabelle, Leroy, Didier, Andenmatten, Nicole, Mäser, Pascal, Wittlin, Sergio
Publicado 2019

Cysteine-Rich Protective Antigen (CyRPA) as promising blood-stage candidate protein for inclusion in a malaria subunit vaccine

por Favuzza, Paola, Dreyer, Anita M, Wittlin, Sergio, Matile, Hugues, Pluschke, Gerd
Publicado 2012

Isothermal Microcalorimetry, a New Tool to Monitor Drug Action against Trypanosoma brucei and Plasmodium falciparum

por Wenzler, Tanja, Steinhuber, Andrea, Wittlin, Sergio, Scheurer, Christian, Brun, Reto, Trampuz, Andrej
Publicado 2012

Ancient Chinese Methods Are Remarkably Effective for the Preparation of Artemisinin-Rich Extracts of Qing Hao with Potent Antimalarial Activity

por Wright, Colin W., Linley, Peter A., Brun, Reto, Wittlin, Sergio, Hsu, Elisabeth
Publicado 2010

In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate

por Baumgärtner, Fabian, Jourdan, Joëlle, Scheurer, Christian, Blasco, Benjamin, Campo, Brice, Mäser, Pascal, Wittlin, Sergio
Publicado 2017

Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

por Potluri, Vijay, Shandil, Radha K., Gavara, R., Sambasivam, Ganesh, Campo, Brice, Wittlin, Sergio, Narayanan, Shridhar
Publicado 2020

The Plasmodium Lactate/H(+) Transporter PfFNT Is Essential and Druggable In Vivo

por Davies, Heledd, Bergmann, Bärbel, Walloch, Philipp, Nerlich, Cornelius, Hansen, Christian, Wittlin, Sergio, Spielmann, Tobias, Treeck, Moritz, Beitz, Eric
Publicado 2023

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

por Delves, Michael, Plouffe, David, Scheurer, Christian, Meister, Stephan, Wittlin, Sergio, Winzeler, Elizabeth A., Sinden, Robert E., Leroy, Didier
Publicado 2012

Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development

por Burgert, Lydia, Rottmann, Matthias, Wittlin, Sergio, Gobeau, Nathalie, Krause, Andreas, Dingemanse, Jasper, Möhrle, Jörg J., Penny, Melissa A.
Publicado 2020

P160 Paracoccidioidomycosis severe: Bizarre presentation in the face

por Azevedo, Conceicao De Maria, Holanda, Rodrigo, Marques, Sirlei, Silva, Raimunda Ribeiro, Nunes, Natália, Wittlin, Bernardo, Santos, Daniel Wagner
Publicado 2022

Monoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel)

por Jourdan, Joëlle, Matile, Hugues, Reift, Ellen, Biehlmaier, Oliver, Dong, Yuxiang, Wang, Xiaofang, Mäser, Pascal, Vennerstrom, Jonathan L., Wittlin, Sergio
Publicado 2015

The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

por Hitz, Eva, Grüninger, Olivia, Passecker, Armin, Wyss, Matthias, Scheurer, Christian, Wittlin, Sergio, Beck, Hans-Peter, Brancucci, Nicolas M. B., Voss, Till S.
Publicado 2021

The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

por Hitz, Eva, Wiedemar, Natalie, Passecker, Armin, Graça, Beatriz A. S., Scheurer, Christian, Wittlin, Sergio, Brancucci, Nicolas M. B., Vakonakis, Ioannis, Mäser, Pascal, Voss, Till S.
Publicado 2021

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

por Moehrle, Joerg J, Duparc, Stephan, Siethoff, Christoph, Giersbergen, Paul L M, Craft, J Carl, Arbe-Barnes, Sarah, Charman, Susan A, Gutierrez, Maria, Wittlin, Sergio, Vennerstrom, Jonathan L
Publicado 2013

Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model

por Kiboi, D.M., Irungu, B.N., Langat, B., Wittlin, S., Brun, R., Chollet, J., Abiodun, O., Nganga, J.K., Nyambati, V.C.S., Rukunga, G.M., Bell, A., Nzila, A.
Publicado 2009