Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

por Fessel, Joshua P., Hamid, Rizwan, Wittmann, Bryan M., Robinson, Linda J., Blackwell, Tom, Tada, Yuji, Tanabe, Nobuhiro, Tatsumi, Koichiro, Hemnes, Anna R., West, James D.
Publicado 2012

Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease

por Rajasekaran, Surender, Bupp, Caleb P, Leimanis-Laurens, Mara, Shukla, Ankit, Russell, Christopher, Junewick, Joseph, Gleason, Emily, VanSickle, Elizabeth A, Edgerly, Yvonne, Wittmann, Bryan M, Prokop, Jeremy W, Bachmann, André S
Publicado 2021

Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine

por Wittmann, Bryan M., Stirdivant, Steven M., Mitchell, Matthew W., Wulff, Jacob E., McDunn, Jonathan E., Li, Zhen, Dennis-Barrie, Aphrihl, Neri, Bruce P., Milburn, Michael V., Lotan, Yair, Wolfert, Robert L.
Publicado 2014

Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis

por Ketchart, Wannarasmi, Smith, Kerri M., Krupka, Tianyi, Wittmann, Bryan M., Hu, Yanduan, Rayman, Patricia A., Doughman, Yong Qiu, Albert, Jeffrey M., Bai, Xiadong, Finke, James H., Xu, Yan, Exner, Agata A., Montano, Monica M.
Publicado 2012

Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults

por Perkins, Bradley A., Caskey, C. Thomas, Brar, Pamila, Dec, Eric, Karow, David S., Kahn, Andrew M., Hou, Ying-Chen Claire, Shah, Naisha, Boeldt, Debbie, Coughlin, Erin, Hands, Gabby, Lavrenko, Victor, Yu, James, Procko, Andrea, Appis, Julia, Dale, Anders M., Guo, Lining, Jönsson, Thomas J., Wittmann, Bryan M., Bartha, Istvan, Ramakrishnan, Smriti, Bernal, Axel, Brewer, James B., Brewerton, Suzanne, Biggs, William H., Turpaz, Yaron, Venter, J. Craig
Publicado 2018

A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

por El-Habr, Elias A., Dubois, Luiz G., Burel-Vandenbos, Fanny, Bogeas, Alexandra, Lipecka, Joanna, Turchi, Laurent, Lejeune, François-Xavier, Coehlo, Paulo Lucas Cerqueira, Yamaki, Tomohiro, Wittmann, Bryan M., Fareh, Mohamed, Mahfoudhi, Emna, Janin, Maxime, Narayanan, Ashwin, Morvan-Dubois, Ghislaine, Schmitt, Charlotte, Verreault, Maité, Oliver, Lisa, Sharif, Ariane, Pallud, Johan, Devaux, Bertrand, Puget, Stéphanie, Korkolopoulou, Penelope, Varlet, Pascale, Ottolenghi, Chris, Plo, Isabelle, Moura-Neto, Vivaldo, Virolle, Thierry, Chneiweiss, Hervé, Junier, Marie-Pierre
Publicado 2016