Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

por Castle, Andrew R., Wohlgemuth, Serene, Arce, Luis, Westaway, David
Publicado 2022

Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly

por Prill, Kendal, Windsor Reid, Pamela, Wohlgemuth, Serene L., Pilgrim, David B.
Publicado 2015

Correction: Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly

por Prill, Kendal, Reid, Pamela Windsor, Wohlgemuth, Serene L., Pilgrim, David B.
Publicado 2016

Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP

por Daude, Nathalie, Wohlgemuth, Serene, Rogaeva, Ekaterina, Farid, A. Hossein, Heaton, Mike, Westaway, David
Publicado 2009

Amyloid Beta Precursor Protein and Prion Protein Have a Conserved Interaction Affecting Cell Adhesion and CNS Development

por Kaiser, Darcy M., Acharya, Moulinath, Leighton, Patricia L. A., Wang, Hao, Daude, Nathalie, Wohlgemuth, Serene, Shi, Beipei, Allison, W. Ted
Publicado 2012

Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high–molecular weight complexes

por Daude, Nathalie, Lau, Agnes, Vanni, Ilaria, Kang, Sang-Gyun, Castle, Andrew R., Wohlgemuth, Serene, Dorosh, Lyudmyla, Wille, Holger, Stepanova, Maria, Westaway, David
Publicado 2022

Susceptibility of Beavers to Chronic Wasting Disease

por Herbst, Allen, Wohlgemuth, Serene, Yang, Jing, Castle, Andrew R., Moreno, Diana Martinez, Otero, Alicia, Aiken, Judd M., Westaway, David, McKenzie, Debbie
Publicado 2022

Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein

por Castle, Andrew R., Kang, Sang-Gyun, Eskandari-Sedighi, Ghazaleh, Wohlgemuth, Serene, Nguyen, My-Anh, Drucker, Daniel J., Mulvihill, Erin E., Westaway, David
Publicado 2022

Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope

por Kang, Sang-Gyun, Han, Zhuang Zhuang, Daude, Nathalie, McNamara, Emily, Wohlgemuth, Serene, Molina-Porcel, Laura, Safar, Jiri G., Mok, Sue-Ann, Westaway, David
Publicado 2021

Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation

por Daude, Nathalie, Kim, Chae, Kang, Sang-Gyun, Eskandari-Sedighi, Ghazaleh, Haldiman, Tracy, Yang, Jing, Fleck, Shelaine C., Gomez-Cardona, Erik, Han, Zhuang Zhuang, Borrego-Ecija, Sergi, Wohlgemuth, Serene, Julien, Olivier, Wille, Holger, Molina-Porcel, Laura, Gelpi, Ellen, Safar, Jiri G., Westaway, David
Publicado 2020

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

por Lau, Agnes, McDonald, Alex, Daude, Nathalie, Mays, Charles E, Walter, Eric D, Aglietti, Robin, Mercer, Robert CC, Wohlgemuth, Serene, van der Merwe, Jacques, Yang, Jing, Gapeshina, Hristina, Kim, Chae, Grams, Jennifer, Shi, Beipei, Wille, Holger, Balachandran, Aru, Schmitt-Ulms, Gerold, Safar, Jiri G, Millhauser, Glenn L, Westaway, David
Publicado 2015

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alle...

por Mercer, Robert C. C., Daude, Nathalie, Dorosh, Lyudmyla, Fu, Ze-Lin, Mays, Charles E., Gapeshina, Hristina, Wohlgemuth, Serene L., Acevedo-Morantes, Claudia Y., Yang, Jing, Cashman, Neil R., Coulthart, Michael B., Pearson, Dawn M., Joseph, Jeffrey T., Wille, Holger, Safar, Jiri G., Jansen, Gerard H., Stepanova, Maria, Sykes, Brian D., Westaway, David
Publicado 2018