pH sensing and regulation in cancer

por Damaghi, Mehdi, Wojtkowiak, Jonathan W., Gillies, Robert J.
Publicado 2013

MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts

por Zhang, Xiaomeng, Wojtkowiak, Jonathan W., Martinez, Gary V., Cornnell, Heather H., Hart, Charles P., Baker, Amanda F., Gillies, Robert
Publicado 2016

Cell-surface markers for colon adenoma and adenocarcinoma

por Sewda, Kamini, Coppola, Domenico, Enkemann, Steven, Yue, Binglin, Kim, Jongphil, Lopez, Alexis S., Wojtkowiak, Jonathan W., Stark, Valerie E., Morse, Brian, Shibata, David, Vignesh, Shivakumar, Morse, David L.
Publicado 2016

Evaluation of the “Steal” Phenomenon on the Efficacy of Hypoxia Activated Prodrug TH-302 in Pancreatic Cancer

por Bailey, Kate M., Cornnell, Heather H., Ibrahim-Hashim, Arig, Wojtkowiak, Jonathan W., Hart, Charles P., Zhang, Xiaomeng, Leos, Rafael, Martinez, Gary V., Baker, Amanda F., Gillies, Robert J.
Publicado 2014

Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane

por Damaghi, Mehdi, Tafreshi, Narges K., Lloyd, Mark C., Sprung, Robert, Estrella, Veronica, Wojtkowiak, Jonathan W., Morse, David L., Koomen, John M., Bui, Marilyn M., Gatenby, Robert A, Gillies, Robert J
Publicado 2015

Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy

por Pillai, Smitha, Mahmud, Iqbal, Mahar, Rohit, Griffith, Crystal, Langsen, Michael, Nguyen, Jonathan, Wojtkowiak, Jonathan W., Swietach, Pawel, Gatenby, Robert A., Bui, Marilyn M., Merritt, Matthew E., McDonald, Patricia, Garrett, Timothy J., Gillies, Robert J.
Publicado 2022

Pyruvate Induces Transient Tumor Hypoxia by Enhancing Mitochondrial Oxygen Consumption and Potentiates the Anti-Tumor Effect of a Hypoxia-Activated Prodrug TH-302

por Takakusagi, Yoichi, Matsumoto, Shingo, Saito, Keita, Matsuo, Masayuki, Kishimoto, Shun, Wojtkowiak, Jonathan W., DeGraff, William, Kesarwala, Aparna H., Choudhuri, Rajani, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Gillies, Robert J., Mitchell, James B., Hart, Charles P., Krishna, Murali C.
Publicado 2014

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302

por Wojtkowiak, Jonathan W, Cornnell, Heather C, Matsumoto, Shingo, Saito, Keita, Takakusagi, Yoichi, Dutta, Prasanta, Kim, Munju, Zhang, Xiaomeng, Leos, Rafael, Bailey, Kate M, Martinez, Gary, Lloyd, Mark C, Weber, Craig, Mitchell, James B, Lynch, Ronald M, Baker, Amanda F, Gatenby, Robert A, Rejniak, Katarzyna A, Hart, Charles, Krishna, Murali C, Gillies, Robert J
Publicado 2015