Ex Vivo Gene Therapy Using Patient iPSC-Derived NSCs Reverses Pathology in the Brain of a Homologous Mouse Model

por Griffin, Tagan A., Anderson, Hayley C., Wolfe, John H.
Publicado 2015

Dysregulation of Gene Expression in a Lysosomal Storage Disease Varies between Brain Regions Implicating Unexpected Mechanisms of Neuropathology

por Parente, Michael K., Rozen, Ramona, Cearley, Cassia N., Wolfe, John H.
Publicado 2012

Quantitative, noninvasive, in vivo longitudinal monitoring of gene expression in the brain by co-AAV transduction with a PET reporter gene

por Yoon, Sea Young, Gay-Antaki, Carlos, Ponde, Datta E, Poptani, Harish, Vite, Charles H, Wolfe, John H
Publicado 2014

Bilateral single-site intracerebral injection of a nonpathogenic herpes simplex virus-1 vector decreases anxiogenic behavior in MPS VII mice

por Liu, Wenpei, Griffin, Gerald, Clarke, Trena, Parente, Michael K, Valentino, Rita J, Wolfe, John H, Fraser, Nigel W
Publicado 2015

Transduction characteristics of alternative adeno-associated virus serotypes in the cat brain by intracisternal delivery

por Hunter, Jacqueline E., Molony, Caitlyn M., Bagel, Jessica H., O’Donnell, Patricia A., Kaler, Stephen G., Wolfe, John H.
Publicado 2022

Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration

por Mor, Danielle E., Tsika, Elpida, Mazzulli, Joseph R., Gould, Neal S., Kim, Hanna, Daniels, Malcolm J., Doshi, Shachee, Gupta, Preetika, Grossman, Jennifer L., Tan, Victor X., Kalb, Robert G., Caldwell, Kim A., Caldwell, Guy A., Wolfe, John H., Ischiropoulos, Harry
Publicado 2017

Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

por Ripolles-Garcia, Ana, Dolgova, Natalia, Phillips, M. Joseph, Savina, Svetlana, Ludwig, Allison L., Stuedemann, Sara A., Nlebedum, Uchenna, Wolfe, John H., Garden, Oliver A., Maminishkis, Arvydas, Amaral, Juan, Bharti, Kapil, Gamm, David M., Aguirre, Gustavo D., Beltran, William A.
Publicado 2022

Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases

por Tremblay, Jacques P, Xiao, Xiao, Aartsma-Rus, Annemieke, Barbas, Carlos, Blau, Helen M, Bogdanove, Adam J, Boycott, Kym, Braun, Serge, Breakefield, Xandra O, Bueren, Juan A, Buschmann, Michael, Byrne, Barry J, Calos, Michele, Cathomen, Toni, Chamberlain, Jeffrey, Chuah, Marinee, Cornetta, Kenneth, Davies, Kay E, Dickson, J George, Duchateau, Philippe, Flotte, Terence R, Gaudet, Daniel, Gersbach, Charles A, Gilbert, Renald, Glorioso, Joseph, Herzog, Roland W, High, Katherine A, Huang, Wenlin, Huard, Johnny, Joung, J Keith, Liu, Depei, Liu, Dexi, Lochmüller, Hanns, Lustig, Lawrence, Martens, Jeffrey, Massie, Bernard, Mavilio, Fulvio, Mendell, Jerry R, Nathwani, Amit, Ponder, Katherine, Porteus, Matthew, Puymirat, Jack, Samulski, Jude, Takeda, Shin'ichi, Thrasher, Adrian, VandenDriessche, Thierry, Wei, Yuquan, Wilson, James M, Wilton, Steve D, Wolfe, John H, Gao, Guangping
Publicado 2013