A phase I, single‐center, open‐label study to investigate the absorption, distribution, metabolism and excretion of encorafenib following a single oral dose of 100 mg [ (14)C] enco...

por Wollenberg, Lance, Hahn, Erik, Williams, Jason, Litwiler, Kevin
Publicado 2023

Effect of Food and a Proton-Pump Inhibitor on the Absorption of Encorafenib: An In Vivo–In Vitro–In Silico Approach

por Piscitelli, Joseph, Hens, Bart, Tomaszewska, Irena, Wollenberg, Lance, Litwiler, Kevin, McAllister, Mark, Reddy, Micaela
Publicado 2023

An exploratory, randomized, parallel-group, open-label, relative bioavailability study with an additional two-period crossover food-effect study exploring the pharmacokinetics of t...

por Wollenberg, Lance A, Corson, Donald T, Nugent, Courtney A, Peterson, Farran L, Ptaszynski, Ann M, Arrigo, Alisha, Mannila, Coralee G, Litwiler, Kevin S, Bell, Stacie J
Publicado 2015