Rapid progression of combined hepatocellular carcinoma and cholangiocarcinoma

por Saboo, Sachin S., Krajewski, Katherine M., Jagannathan, Jyothi P., O’Regan, Kevin N., Odze, Robert, Ramaiya, Nikhil, Wolpin, Brian M.
Publicado 2011

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

por Cleary, James M., Rouaisnel, Betty, Daina, Antoine, Raghavan, Srivatsan, Roller, Lauren A., Huffman, Brandon M., Singh, Harshabad, Wen, Patrick Y., Bardeesy, Nabeel, Zoete, Vincent, Wolpin, Brian M., Losman, Julie-Aurore
Publicado 2022

Emerging Role of Targeted Therapy in Metastatic Pancreatic Adenocarcinoma

por Huffman, Brandon M., Ellis, Haley, Jordan, Alexander C., Freed-Pastor, William A., Perez, Kimberly, Rubinson, Douglas A., Sethi, Nilay, Singh, Harshabad, Surana, Rishi, Wolpin, Brian M., Aguirre, Andrew J., Cleary, James M.
Publicado 2022

Physical activity in older adults with metastatic gastrointestinal cancer: a pilot and feasibility study

por Brown, Justin C, Brighton, Elizabeth, Campbell, Nancy, McCleary, Nadine J, Abrams, Thomas A, Cleary, James M, Enzinger, Peter C, Ng, Kimmie, Rubinson, Douglas, Wolpin, Brian M, Yurgelun, Matthew B, Meyerhardt, Jeffrey A
Publicado 2022

Acid-suppressive medications and risk of colorectal cancer: results from three large prospective cohort studies

por Babic, Ana, Zhang, Xuehong, Morales-Oyarvide, Vicente, Yuan, Chen, Khalaf, Natalia, Khalili, Hamed, Lochhead, Paul, Chan, Andrew T., Ogino, Shuji, Wolpin, Brian M., Wu, Kana, Fuchs, Charles S., Giovannucci, Edward L., Stampfer, Meir J., Ng, Kimmie
Publicado 2020

Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer

por Blise, Katie E., Sivagnanam, Shamilene, Betts, Courtney B., Betre, Konjit, Kirchberger, Nell, Tate, Benjamin, Furth, Emma E., Dias Costa, Andressa, Nowak, Jonathan A., Wolpin, Brian M., Vonderheide, Robert H., Goecks, Jeremy, Coussens, Lisa M., Byrne, Katelyn T.
Publicado 2023

Pancreatic cancer is associated with medication changes prior to clinical diagnosis

por Zhang, Yin, Wang, Qiao-Li, Yuan, Chen, Lee, Alice A., Babic, Ana, Ng, Kimmie, Perez, Kimberly, Nowak, Jonathan A., Lagergren, Jesper, Stampfer, Meir J., Giovannucci, Edward L., Sander, Chris, Rosenthal, Michael H., Kraft, Peter, Wolpin, Brian M.
Publicado 2023

Critical role for arginase 2 in obesity-associated pancreatic cancer

por Zaytouni, Tamara, Tsai, Pei-Yun, Hitchcock, Daniel S., DuBois, Cory D., Freinkman, Elizaveta, Lin, Lin, Morales-Oyarvide, Vicente, Lenehan, Patrick J., Wolpin, Brian M., Mino-Kenudson, Mari, Torres, Eduardo M., Stylopoulos, Nicholas, Clish, Clary B., Kalaany, Nada Y.
Publicado 2017

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

por Patterson-Fortin, Jeffrey, Jadhav, Heta, Pantelidou, Constantia, Phan, Tin, Grochala, Carter, Mehta, Anita K., Guerriero, Jennifer L., Wulf, Gerburg M., Wolpin, Brian M., Stanger, Ben Z., Aguirre, Andrew J., Cleary, James M., D’Andrea, Alan D., Shapiro, Geoffrey I.
Publicado 2023

Phase I Study of Cetuximab, Irinotecan, and Vandetanib (ZD6474) as Therapy for Patients with Previously Treated Metastastic Colorectal Cancer

por Meyerhardt, Jeffrey A., Ancukiewicz, Marek, Abrams, Thomas A., Schrag, Deborah, Enzinger, Peter C., Chan, Jennifer A., Kulke, Matthew H., Wolpin, Brian M., Goldstein, Michael, Blaszkowsky, Lawrence, Zhu, Andrew X., Elliott, Meaghan, Regan, Eileen, Jain, Rakesh K., Duda, Dan G.
Publicado 2012

Family history of cancer, Ashkenazi Jewish ancestry, and pancreatic cancer risk

por Hamada, Tsuyoshi, Yuan, Chen, Yurgelun, Matthew B., Perez, Kimberly, Khalaf, Natalia, Morales-Oyarvide, Vicente, Babic, Ana, Nowak, Jonathan A., Rubinson, Douglas A., Giannakis, Marios, Ng, Kimmie, Kraft, Peter, Stampfer, Meir J., Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji, Wolpin, Brian M.
Publicado 2019

Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of meta...

por Noel, Marcus, O’Reilly, Eileen M., Wolpin, Brian M., Ryan, David P., Bullock, Andrea J., Britten, Carolyn D., Linehan, David C., Belt, Brian A., Gamelin, Eric C., Ganguly, Bishu, Yin, Donghua, Joh, Tenshang, Jacobs, Ira A., Taylor, Carrie T., Lowery, Maeve A.
Publicado 2019

Influence of dietary insulin scores on survival in colorectal cancer patients

por Yuan, Chen, Bao, Ying, Sato, Kaori, Nimptsch, Katharina, Song, Mingyang, Brand-Miller, Jennie C, Morales-Oyarvide, Vicente, Zoltick, Emilie S, Keum, NaNa, Wolpin, Brian M, Meyerhardt, Jeffrey A, Chan, Andrew T, Willett, Walter C, Stampfer, Meir J, Wu, Kana, Giovannucci, Edward L, Fuchs, Charles S, Ng, Kimmie
Publicado 2017

Effect of a MUC5AC Antibody (NPC-1C) Administered With Second-Line Gemcitabine and Nab-Paclitaxel on the Survival of Patients With Advanced Pancreatic Ductal Adenocarcinoma: A Rand...

por Huffman, Brandon M., Basu Mallick, Atrayee, Horick, Nora K., Wang-Gillam, Andrea, Hosein, Peter Joel, Morse, Michael A., Beg, Muhammad Shaalan, Murphy, Janet E., Mavroukakis, Sharon, Zaki, Anjum, Schlechter, Benjamin L., Sanoff, Hanna, Manz, Christopher, Wolpin, Brian M., Arlen, Philip, Lacy, Jill, Cleary, James M.
Publicado 2023

USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

por Perurena, Naiara, Lock, Rebecca, Davis, Rachel A., Raghavan, Srivatsan, Pilla, Natalie F., Ng, Raymond, Loi, Patrick, Guild, Caroline J., Miller, Abigail L., Sicinska, Ewa, Cleary, James M., Rubinson, Douglas A., Wolpin, Brian M., Gray, Nathanael S., Santagata, Sandro, Hahn, William C., Morton, Jennifer P., Sansom, Owen J., Aguirre, Andrew J., Cichowski, Karen
Publicado 2023

Multicenter randomized controlled trial of neoadjuvant chemoradiotherapy alone or in combination with pembrolizumab in patients with resectable or borderline resectable pancreatic...

por Katz, Matthew H G, Petroni, Gina R, Bauer, Todd, Reilley, Matthew J, Wolpin, Brian M, Stucky, Chee-Chee, Bekaii-Saab, Tanios S, Elias, Rawad, Merchant, Nipun, Dias Costa, Andressa, Lenehan, Patrick, Cardot-Ruffino, Victoire, Rodig, Scott, Pfaff, Kathleen, Dougan, Stephanie K, Nowak, Jonathan Andrew, Varadhachary, Gauri R, Slingluff, Craig L, Rahma, Osama
Publicado 2023

Helicobacter pylori Seropositivity, ABO Blood Type, and Pancreatic Cancer Risk From 5 Prospective Cohorts

por Lee, Alice A., Wang, Qiao-Li, Kim, Jihye, Babic, Ana, Zhang, Xuehong, Perez, Kimberly, Ng, Kimmie, Nowak, Jonathan, Rifai, Nader, Sesso, Howard D., Buring, Julie E., Anderson, Garnet L., Wactawski-Wende, Jean, Wallace, Robert, Manson, JoAnn E., Giovannucci, Edward L., Stampfer, Meir J., Kraft, Peter, Fuchs, Charles S., Yuan, Chen, Wolpin, Brian M.
Publicado 2023

Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

por McFarland, James M., Paolella, Brenton R., Warren, Allison, Geiger-Schuller, Kathryn, Shibue, Tsukasa, Rothberg, Michael, Kuksenko, Olena, Colgan, William N., Jones, Andrew, Chambers, Emily, Dionne, Danielle, Bender, Samantha, Wolpin, Brian M., Ghandi, Mahmoud, Tirosh, Itay, Rozenblatt-Rosen, Orit, Roth, Jennifer A., Golub, Todd R., Regev, Aviv, Aguirre, Andrew J., Vazquez, Francisca, Tsherniak, Aviad
Publicado 2020

A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

por Placido, Davide, Yuan, Bo, Hjaltelin, Jessica X., Zheng, Chunlei, Haue, Amalie D., Chmura, Piotr J., Yuan, Chen, Kim, Jihye, Umeton, Renato, Antell, Gregory, Chowdhury, Alexander, Franz, Alexandra, Brais, Lauren, Andrews, Elizabeth, Marks, Debora S., Regev, Aviv, Ayandeh, Siamack, Brophy, Mary T., Do, Nhan V., Kraft, Peter, Wolpin, Brian M., Rosenthal, Michael H., Fillmore, Nathanael R., Brunak, Søren, Sander, Chris
Publicado 2023

Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells

por Gu, Mancang, Nishihara, Reiko, Chen, Yang, Li, Wanwan, Shi, Yan, Masugi, Yohei, Hamada, Tsuyoshi, Kosumi, Keisuke, Liu, Li, da Silva, Annacarolina, Nowak, Jonathan A., Twombly, Tyler, Du, Chunxia, Koh, Hideo, Li, Wenbin, Meyerhardt, Jeffrey A., Wolpin, Brian M., Giannakis, Marios, Aguirre, Andrew J., Bass, Adam J., Drew, David A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Publicado 2017