Keeping ribosomal DNA intact: a repeating challenge

por Warmerdam, Daniël O., Wolthuis, Rob M. F.
Publicado 2018

Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression

por Lindqvist, Arne, van Zon, Wouter, Karlsson Rosenthal, Christina, Wolthuis, Rob M. F
Publicado 2007

The APC/C recruits cyclin B1–Cdk1–Cks in prometaphase before D box recognition to control mitotic exit

por van Zon, Wouter, Ogink, Janneke, ter Riet, Bas, Medema, René H., te Riele, Hein, Wolthuis, Rob M.F.
Publicado 2010

In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region

por Kohabir, Kavish A.V., Nooi, Lars O., Brink, Arjen, Brakenhoff, Ruud H., Sistermans, Erik A., Wolthuis, Rob M.F.
Publicado 2023

ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data

por Tissier, Renaud L. M., Schie, Janne J. M. van, Wolthuis, Rob M. F., Lange, Job de, Menezes, Renée de
Publicado 2023

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities

por van Dongen, Jeanne E., Berendsen, Johanna T.W., Steenbergen, Renske D.M., Wolthuis, Rob M.F., Eijkel, Jan C.T., Segerink, Loes I.
Publicado 2020

The Small Gtpase, Rap1, Mediates Cd31-Induced Integrin Adhesion

por Reedquist, Kris A., Ross, Ewan, Koop, Elianne A., Wolthuis, Rob M.F., Zwartkruis, Fried J.T., van Kooyk, Yvette, Salmon, Mike, Buckley, Christopher D., Bos, Johannes L.
Publicado 2000

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

por Faramarz, Atiq, Balk, Jesper A., van Schie, Janne J. M., Oostra, Anneke B., Ghandour, Cherien A., Rooimans, Martin A., Wolthuis, Rob M. F., de Lange, Job
Publicado 2020

Polo-Like Kinase-1 Controls Aurora A Destruction by Activating APC/C-Cdh1

por van Leuken, Renske, Clijsters, Linda, van Zon, Wouter, Lim, Dan, Yao, XueBiao, Wolthuis, Rob M. F., Yaffe, Michael B., Medema, René H., van Vugt, Marcel A. T. M.
Publicado 2009

No evidence for increased prevalence of colorectal carcinoma in 399 Dutch patients with Birt-Hogg-Dubé syndrome

por van de Beek, Irma, Glykofridis, Iris E., Wolthuis, Rob M. F., Gille, Hans J. J. P., Johannesma, Paul C., Meijers-Heijboer, Hanne E. J., Moorselaar, R. Jeroen A. van, Houweling, Arjan C.
Publicado 2019

Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death

por van Harten, Anne M., Buijze, Marijke, van der Mast, Richard, Rooimans, Martin A., Martens-de Kemp, Sanne R., Bachas, Costa, Brink, Arjen, Stigter-van Walsum, Marijke, Wolthuis, Rob M. F., Brakenhoff, Ruud H.
Publicado 2019

Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair

por van de Vrugt, Henri J., Harmsen, Tim, Riepsaame, Joey, Alexantya, Georgina, van Mil, Saskia E., de Vries, Yne, Bin Ali, Rahmen, Huijbers, Ivo J., Dorsman, Josephine C., Wolthuis, Rob M. F., te Riele, Hein
Publicado 2019

Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines

por Glykofridis, Iris E., Henneman, Alex A., Balk, Jesper A., Goeij-de Haas, Richard, Westland, Denise, Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Boekhout, Michiel, Zwartkruis, Fried J.T., Wolthuis, Rob M.F., Jimenez, Connie R.
Publicado 2022

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

por Bachas, Costa, Hodzic, Jasmina, van der Mijn, Johannes C., Stoepker, Chantal, Verheul, Henk M. W., Wolthuis, Rob M. F., Felley-Bosco, Emanuela, van Wieringen, Wessel N., van Beusechem, Victor W., Brakenhoff, Ruud H., de Menezes, Renée X.
Publicado 2018

Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition

por van Harten, Anne M., de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Ganzevles, Sonja H., Hunter, Keith D., Leemans, C. René, van Beusechem, Victor W., Wolthuis, Rob M. F., de Menezes, Renée X., Brakenhoff, Ruud H.
Publicado 2020

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function

por de Lange, Job, Faramarz, Atiq, Oostra, Anneke B., de Menezes, Renee X., van der Meulen, Ida H., Rooimans, Martin A., Rockx, Davy A., Brakenhoff, Ruud H., van Beusechem, Victor W., King, Randall W., de Winter, Johan P., Wolthuis, Rob M. F.
Publicado 2015

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma

por Pai, Govind, Roohollahi, Khashayar, Rockx, Davy, de Jong, Yvonne, Stoepker, Chantal, Pennings, Charlotte, Rooimans, Martin, Vriend, Lianne, Piersma, Sander, Jimenez, Connie R., De Menezes, Renee X., Van Beusechem, Victor W., Brakenhoff, Ruud H., Te Riele, Hein, Wolthuis, Rob M. F., Dorsman, Josephine C.
Publicado 2023

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin

por van Schie, Janne J M, de Lint, Klaas, Molenaar, Thom M, Moronta Gines, Macarena, Balk, Jesper A, Rooimans, Martin A, Roohollahi, Khashayar, Pai, Govind M, Borghuis, Lauri, Ramadhin, Anisha R, Corazza, Francesco, Dorsman, Josephine C, Wendt, Kerstin S, Wolthuis, Rob M F, de Lange, Job
Publicado 2023

Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation

por Carvalhal, Sara, Bader, Ingrid, Rooimans, Martin A., Oostra, Anneke B., Balk, Jesper A., Feichtinger, René G., Beichler, Christine, Speicher, Michael R., van Hagen, Johanna M., Waisfisz, Quinten, van Haelst, Mieke, Bruijn, Martijn, Tavares, Alexandra, Mayr, Johannes A., Wolthuis, Rob M. F., Oliveira, Raquel A., de Lange, Job
Publicado 2022

Combined germline pathogenic variants in FLCN and TP53 are associated with early onset renal cell carcinoma and brain tumors

por van de Beek, Irma, Glykofridis, Iris E., Wagner, Anja, den Toom, Dorine T., Bongers, Ernie M. H. F., van Leenders, Geert J. L. H., Johannesma, Paul C., Meijers‐Heijboer, Hanne E. J., Wolthuis, Rob M. F., van Steensel, Maurice A. M., Dubbink, Hendrikus J., Houweling, Arjan C.
Publicado 2022