Exploring aging interventions in human brain organoids

por Aguado, Julio, Wolvetang, Ernst J.
Publicado 2022

Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells

por Ovchinnikov, Dmitry A., Wolvetang, Ernst J.
Publicado 2014

CRISPR-Cas9 Direct Fusions for Improved Genome Editing via Enhanced Homologous Recombination

por Tabassum, Tahmina, Pietrogrande, Giovanni, Healy, Michael, Wolvetang, Ernst J.
Publicado 2023

Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease

por Tracey, Timothy J., Steyn, Frederik J., Wolvetang, Ernst J., Ngo, Shyuan T.
Publicado 2018

Klotho inhibits neuronal senescence in human brain organoids

por Shaker, Mohammed R., Aguado, Julio, Chaggar, Harman Kaur, Wolvetang, Ernst J.
Publicado 2021

The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons

por Ovchinnikov, Dmitry A., Korn, Othmar, Virshup, Isaac, Wells, Christine A., Wolvetang, Ernst J.
Publicado 2018

Rapid and Efficient Generation of Myelinating Human Oligodendrocytes in Organoids

por Shaker, Mohammed R., Pietrogrande, Giovanni, Martin, Sally, Lee, Ju-Hyun, Sun, Woong, Wolvetang, Ernst J.
Publicado 2021

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

por Hasegawa, Yu, Taylor, Deanne, Ovchinnikov, Dmitry A., Wolvetang, Ernst J., de Torrenté, Laurence, Mar, Jessica C.
Publicado 2015

TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation

por Thakar, Nilay Y., Ovchinnikov, Dmitry A., Hastie, Marcus L., Kobe, Bostjan, Gorman, Jeffrey J., Wolvetang, Ernst J.
Publicado 2015

Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids

por Aguado, Julio, Chaggar, Harman K., Gómez‐Inclán, Cecilia, Shaker, Mohammed R., Leeson, Hannah C., Mackay‐Sim, Alan, Wolvetang, Ernst J.
Publicado 2021

Microbioreactor Arrays for Full Factorial Screening of Exogenous and Paracrine Factors in Human Embryonic Stem Cell Differentiation

por Titmarsh, Drew M., Hudson, James E., Hidalgo, Alejandro, Elefanty, Andrew G., Stanley, Edouard G., Wolvetang, Ernst J., Cooper-White, Justin J.
Publicado 2012

Direct Comparison of Four Hematopoietic Differentiation Methods from Human Induced Pluripotent Stem Cells

por Tursky, Melinda L., Loi, To Ha, Artuz, Crisbel M., Alateeq, Suad, Wolvetang, Ernst J., Tao, Helen, Ma, David D., Molloy, Timothy J.
Publicado 2020

Protocol for generating embedding-free brain organoids enriched with oligodendrocytes

por Al-mhanawi, Bahaa, Marti, Marta Boira, Morrison, Sean D., Gupta, Pallavi, Alani, Maath, Noakes, Peter G., Wolvetang, Ernst J., Shaker, Mohammed R.
Publicado 2023

Neural Epidermal Growth Factor-Like Like Protein 2 Is Expressed in Human Oligodendroglial Cell Types

por Shaker, Mohammed R., Kahtan, Amna, Prasad, Renuka, Lee, Ju-Hyun, Pietrogrande, Giovanni, Leeson, Hannah C., Sun, Woong, Wolvetang, Ernst J., Slonchak, Andrii
Publicado 2022

Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation

por Salvador-Palomeque, Carmen, Sanchez-Luque, Francisco J., Fortuna, Patrick R. J., Ewing, Adam D., Wolvetang, Ernst J., Richardson, Sandra R., Faulkner, Geoffrey J.
Publicado 2019

Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development

por Glass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H., Cooper-White, Justin J.
Publicado 2020

Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays

por Titmarsh, Drew M., Glass, Nick R., Mills, Richard J., Hidalgo, Alejandro, Wolvetang, Ernst J., Porrello, Enzo R., Hudson, James E., Cooper-White, Justin J.
Publicado 2016

Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells

por Bellmaine, Stephanie F, Ovchinnikov, Dmitry A, Manallack, David T, Cuddy, Claire E, Elefanty, Andrew G, Stanley, Edouard G, Wolvetang, Ernst J, Williams, Spencer J, Pera, Martin
Publicado 2017

Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks

por Nayler, Sam P., Powell, Joseph E., Vanichkina, Darya P., Korn, Othmar, Wells, Christine A., Kanjhan, Refik, Sun, Jian, Taft, Ryan J., Lavin, Martin F., Wolvetang, Ernst J.
Publicado 2017

A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells

por Przepiorski, Aneta, Sander, Veronika, Tran, Tracy, Hollywood, Jennifer A., Sorrenson, Brie, Shih, Jen-Hsing, Wolvetang, Ernst J., McMahon, Andrew P., Holm, Teresa M., Davidson, Alan J.
Publicado 2018