RNAseq-based gene expression profiling of the Anopheles funestus pyrethroid-resistant strain FUMOZ highlights the predominant role of the duplicated CYP6P9a/b cytochrome P450s

por Wondji, Charles S, Hearn, Jack, Irving, Helen, Wondji, Murielle J, Weedall, Gareth
Publicado 2021

Pyrethroid Resistance in the Major Malaria Vector Anopheles funestus is Exacerbated by Overexpression and Overactivity of the P450 CYP6AA1 Across Africa

por Ibrahim, Sulaiman S., Amvongo-Adjia, Nathalie, Wondji, Murielle J., Irving, Helen, Riveron, Jacob M., Wondji, Charles S.
Publicado 2018

Bionomics and insecticides resistance profiling of malaria vectors at a selected site for experimental hut trials in central Cameroon

por Menze, Benjamin D., Wondji, Murielle J., Tchapga, William, Tchoupo, Micareme, Riveron, Jacob M., Wondji, Charles S.
Publicado 2018

Combined over-expression of two cytochrome P450 genes exacerbates the fitness cost of pyrethroid resistance in the major African malaria vector Anopheles funestus

por Tchouakui, Magellan, Mugenzi, Leon M.J., Wondji, Murielle J., Tchoupo, Micareme, Njiokou, Flobert, Wondji, Charles S.
Publicado 2021

A 6.5kb Intergenic Structural Variation Exacerbates the Fitness Cost of P450-Based Metabolic Resistance in the Major African Malaria Vector Anopheles funestus

por Tchouakui, Magellan, Mugenzi, Leon M. J., Wondji, Murielle J., Tchoupo, Micareme, Njiokou, Flobert, Wondji, Charles S.
Publicado 2022

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector Anopheles funestus but PBO-Based Olyse...

por Menze, Benjamin D., Mugenzi, Leon M. J., Tchouakui, Magellan, Wondji, Murielle J., Tchoupo, Micareme, Wondji, Charles S.
Publicado 2022

CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria Vector Anopheles funestus Reveal Contemporary Barriers to Gene Flow

por Djuicy, Delia Doreen, Hearn, Jack, Tchouakui, Magellan, Wondji, Murielle J., Irving, Helen, Okumu, Fredros O., Wondji, Charles S.
Publicado 2020

A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon

por Fadel, Amen N., Ibrahim, Sulaiman S., Tchouakui, Magellan, Terence, Ebai, Wondji, Murielle J., Tchoupo, Micareme, Wanji, Samuel, Wondji, Charles S.
Publicado 2019

Genome-Wide Transcription and Functional Analyses Reveal Heterogeneous Molecular Mechanisms Driving Pyrethroids Resistance in the Major Malaria Vector Anopheles funestus Across Afr...

por Riveron, Jacob M., Ibrahim, Sulaiman S., Mulamba, Charles, Djouaka, Rousseau, Irving, Helen, Wondji, Murielle J., Ishak, Intan H., Wondji, Charles S.
Publicado 2017

Genetic Diversity of Cytochrome P450s CYP6M2 and CYP6P4 Associated with Pyrethroid Resistance in the Major Malaria Vectors Anopheles coluzzii and Anopheles gambiae from Yaoundé, Ca...

por Fotso-Toguem, Yvan, Tene-Fossog, Billy, Mugenzi, Leon M. J., Wondji, Murielle J., Njiokou, Flobert, Ranson, Hilary, Wondji, Charles S.
Publicado 2022

High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic

por Ibrahim, Sulaiman S., Fadel, Amen N., Tchouakui, Magellan, Terence, Ebai, Wondji, Murielle J., Tchoupo, Micareme, Kérah-Hinzoumbé, Clement, Wanji, Samuel, Wondji, Charles S.
Publicado 2019

Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy

por Tchouakui, Magellan, Mugenzi, Leon M. J., D. Menze, Benjamin, Khaukha, Jude N. T., Tchapga, Williams, Tchoupo, Micareme, Wondji, Murielle J., Wondji, Charles S.
Publicado 2021

The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus

por Mugenzi, Leon M. J., A. Tekoh, Theofelix, S. Ibrahim, Sulaiman, Muhammad, Abdullahi, Kouamo, Mersimine, Wondji, Murielle J., Irving, Helen, Hearn, Jack, Wondji, Charles S.
Publicado 2023

Correction: Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus

por Tchouakui, Magellan, Riveron Miranda, Jacob, Mugenzi, Leon M. J., Djonabaye, Doumani, Wondji, Murielle J., Tchoupo, Micareme, Tchapga, Williams, Njiokou, Flobert, Wondji, Charles S.
Publicado 2020

Marked aggravation of pyrethroid resistance in major malaria vectors in Malawi between 2014 and 2021 is partly linked with increased expression of P450 alleles

por Menze, Benjamin D., Tchouakui, Magellan, Mugenzi, Leon M. J., Tchapga, Williams, Tchoupo, Micareme, Wondji, Murielle J., Chiumia, Martin, Mzilahowa, Themba, Wondji, Charles S.
Publicado 2022

An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector Anopheles funestus Reveals a Loss of Bed Nets Efficacy Associated with GSTe2 Metabol...

por Menze, Benjamin D., Kouamo, Mersimine F., Wondji, Murielle J., Tchapga, Williams, Tchoupo, Micareme, Kusimo, Michael O., Mouhamadou, Chouaibou S., Riveron, Jacob M., Wondji, Charles S.
Publicado 2020

Escalation of Pyrethroid Resistance in the Malaria Vector Anopheles funestus Induces a Loss of Efficacy of Piperonyl Butoxide–Based Insecticide-Treated Nets in Mozambique

por Riveron, Jacob M, Huijben, Silvie, Tchapga, Williams, Tchouakui, Magellan, Wondji, Murielle J, Tchoupo, Micareme, Irving, Helen, Cuamba, Nelson, Maquina, Mara, Paaijmans, Krijn, Wondji, Charles S
Publicado 2019

Xeno-monitoring of molecular drivers of artemisinin and partner drug resistance in P. falciparum populations in malaria vectors across Cameroon

por Nkemngo, Francis N., Mugenzi, Leon M.J., Tchouakui, Magellan, Nguiffo-Nguete, Daniel, Wondji, Murielle J., Mbakam, Bertrand, Tchoupo, Micareme, Ndo, Cyrille, Wanji, Samuel, Wondji, Charles S.
Publicado 2022

A marker of glutathione S-transferase-mediated resistance to insecticides is associated with higher Plasmodium infection in the African malaria vector Anopheles funestus

por Tchouakui, Magellan, Chiang, Mu-Chun, Ndo, Cyrille, Kuicheu, Carine K., Amvongo-Adjia, Nathalie, Wondji, Murielle J., Tchoupo, Micareme, Kusimo, Michael O., Riveron, Jacob M., Wondji, Charles S.
Publicado 2019

Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus

por Mugenzi, Leon M. J., Menze, Benjamin D., Tchouakui, Magellan, Wondji, Murielle J., Irving, Helen, Tchoupo, Micareme, Hearn, Jack, Weedall, Gareth D., Riveron, Jacob M., Wondji, Charles S.
Publicado 2019