Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice

por Chan, Elizabeth S, Chen, Christopher, Cole, Gregory M, Wong, Boon-Seng
Publicado 2015

Expression of human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver

por Ong, Qi-Rui, Chan, Elizabeth S., Lim, Mei-Li, Wong, Boon-Seng
Publicado 2014

Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice

por Yong, Shan-May, Lim, Mei-Li, Low, Chian-Ming, Wong, Boon-Seng
Publicado 2014

Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice

por Ong, Qi-Rui, Chan, Elizabeth S., Lim, Mei-Li, Cole, Gregory M., Wong, Boon-Seng
Publicado 2014

ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer’s disease mouse model

por Chan, Elizabeth S., Shetty, Mahesh Shivarama, Sajikumar, Sreedharan, Chen, Christopher, Soong, Tuck Wah, Wong, Boon-Seng
Publicado 2016

Effectiveness of home-based, non-exercise interventions for dementia: A systematic review

por Tan, Davynn Gim Hoon, Boo, Belinda Melody Bernadette, Chong, Cheyenne Shuen, Tan, Megan Michelle Ling-Li, Wong, Boon-Seng
Publicado 2022

Serum IL-8 is a marker of white-matter hyperintensities in patients with Alzheimer's disease

por Zhu, Yanan, Chai, Yuek Ling, Hilal, Saima, Ikram, M. Kamran, Venketasubramanian, Narayanaswamy, Wong, Boon-Seng, Chen, Christopher P., Lai, Mitchell K.P.
Publicado 2017

A Pilot Study to Examine the Correlation between Cognition and Blood Biomarkers in a Singapore Chinese Male Cohort with Type 2 Diabetes Mellitus

por Goh, Deborah Amanda, Dong, Yanhong, Lee, Wah Yean, Koay, Way Inn, Tay, Stephen Ziyang, Soon, Danny, Chen, Christopher, Brittain, Claire Frances, Lowe, Stephen Loucian, Wong, Boon-Seng
Publicado 2014

Enterovirus 71 infection of motor neuron-like NSC-34 cells undergoes a non-lytic exit pathway

por Too, Issac Horng Khit, Yeo, Huimin, Sessions, October Michael, Yan, Benedict, Libau, Eshele Anak, Howe, Josephine L. C., Lim, Ze Qin, Suku-Maran, Shalini, Ong, Wei-Yi, Chua, Kaw Bing, Wong, Boon Seng, Chow, Vincent T. K., Alonso, Sylvie
Publicado 2016