Mutation hotspots in cis-regulatory regions in cancer

por Poulos, Rebecca C., Wong, Jason W. H.
Publicado 2016

Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteome

por Ng, John Y., Boelen, Lies, Wong, Jason W. H.
Publicado 2013

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes

por Poulos, Rebecca C., Olivier, Jake, Wong, Jason W.H.
Publicado 2017

Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples

por Ma, Shiyong, Menon, Ranjeeta, Poulos, Rebecca C., Wong, Jason W.H.
Publicado 2017

BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells

por Chacon, Diego, Beck, Dominik, Perera, Dilmi, Wong, Jason W. H., Pimanda, John E.
Publicado 2014

The search for cis-regulatory driver mutations in cancer genomes

por Poulos, Rebecca C., Sloane, Mathew A., Hesson, Luke B., Wong, Jason W. H.
Publicado 2015

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations

por Poulos, Rebecca C., Wong, Yuen T., Ryan, Regina, Pang, Herbert, Wong, Jason W. H.
Publicado 2018

Identification of allosteric disulfides from labile bonds in X-ray structures

por Pijning, Aster E., Chiu, Joyce, Yeo, Reichelle X., Wong, Jason W. H., Hogg, Philip J.
Publicado 2018

Deficiency of replication-independent DNA mismatch repair drives a 5-methylcytosine deamination mutational signature in cancer

por Fang, Hu, Zhu, Xiaoqiang, Yang, Haocheng, Oh, Jieun, Barbour, Jayne A., Wong, Jason W. H.
Publicado 2021

Integrative processing of untargeted metabolomic and lipidomic data using MultiABLER

por Lee, Ian C.H., Tumanov, Sergey, Wong, Jason W.H., Stocker, Roland, Ho, Joshua W.K.
Publicado 2023

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

por Fang, Hu, Barbour, Jayne A., Poulos, Rebecca C., Katainen, Riku, Aaltonen, Lauri A., Wong, Jason W. H.
Publicado 2020

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

por Zeraati, Mahdi, Moye, Aaron L., Wong, Jason W. H., Perera, Dilmi, Cowley, Mark J., Christ, Daniel U., Bryan, Tracy M., Dinger, Marcel E.
Publicado 2017

A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients

por Zhu, Xiaoqiang, Tian, Xianglong, Ji, Linhua, Zhang, Xinyu, Cao, Yingying, Shen, Chaoqin, Hu, Ye, Wong, Jason W. H., Fang, Jing-Yuan, Hong, Jie, Chen, Haoyan
Publicado 2021

Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing

por Poulos, Rebecca C, Perera, Dilmi, Packham, Deborah, Shah, Anushi, Janitz, Caroline, Pimanda, John E, Hawkins, Nicholas, Ward, Robyn L, Hesson, Luke B, Wong, Jason W H
Publicado 2019

Repurposing Azacitidine and Carboplatin to Prime Immune Checkpoint Blockade–resistant Melanoma for Anti-PD-L1 Rechallenge

por van der Westhuizen, Andre, Lyle, Megan, Graves, Moira C., Zhu, Xiaoqiang, Wong, Jason W. H., Cornall, Kerrie, Ren, Shu, Pugliese, Leanna, Levy, Richard, Majid, Adeeb, Vilain, Ricardo E., Bowden, Nikola A.
Publicado 2022

Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration

por Krilis, Matthew, Qi, Miao, Madigan, Michele C., Wong, Jason W. H., Abdelatti, Mahmoud, Guymer, Robyn H., Whitelock, John, McCluskey, Peter, Zhang, Peng, Qi, Jian, Hunyor, Alex P., Krilis, Steven A., Giannakopoulos, Bill
Publicado 2017

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network

por Unnikrishnan, Ashwin, Guan, Yi F., Huang, Yizhou, Beck, Dominik, Thoms, Julie A. I., Peirs, Sofie, Knezevic, Kathy, Ma, Shiyong, de Walle, Inge V., de Jong, Ineke, Ali, Zara, Zhong, Ling, Raftery, Mark J., Taghon, Tom, Larsson, Jonas, MacKenzie, Karen L., Van Vlierberghe, Pieter, Wong, Jason W. H., Pimanda, John E.
Publicado 2016

The non-coding RNA landscape of human hematopoiesis and leukemia

por Schwarzer, Adrian, Emmrich, Stephan, Schmidt, Franziska, Beck, Dominik, Ng, Michelle, Reimer, Christina, Adams, Felix Ferdinand, Grasedieck, Sarah, Witte, Damian, Käbler, Sebastian, Wong, Jason W. H., Shah, Anushi, Huang, Yizhou, Jammal, Razan, Maroz, Aliaksandra, Jongen-Lavrencic, Mojca, Schambach, Axel, Kuchenbauer, Florian, Pimanda, John E., Reinhardt, Dirk, Heckl, Dirk, Klusmann, Jan-Henning
Publicado 2017

Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies

por Fang, Hu, Yan, Helen H. N., Bilardi, Rebecca A., Flensburg, Christoffer, Yang, Haocheng, Barbour, Jayne A., Siu, Hoi Cheong, Turski, Michelle, Chew, Edward, Xu, Zhen, Lam, Siu T., Sharma, Rakesh, Xu, Mengya, Li, Junshi, Ip, Ho W., Cheung, Carol Y. M., Huen, Michael S. Y., Sweet-Cordero, E. Alejandro, Majewski, Ian J., Leung, Suet Y., Wong, Jason W. H.
Publicado 2022

The impact of the multi-disciplinary molecular tumour board and integrative next generation sequencing on clinical outcomes in advanced solid tumours

por El Helali, Aya, Lam, Tai-Chung, Ko, Elaine Yee-Ling, Shih, David J.H., Chan, Chun Kau, Wong, Charlene H.L., Wong, Jason W.H., Cheung, Lydia W.T., Lau, Johnny K.S., Liu, Anthony P.Y., Chan, Ann S.Y., Loong, Herbert H., Lam, Stephen Tak Sum, Chan, Godfrey Chi-Fung, Lee, Victor H.F., Yuen, Kwok Keung, Ng, Wai-Tong, Lee, Anne W.M., Ma, Edmond S.K.
Publicado 2023