The structural integrity of the membrane-embedded bacterial division complex FtsQBL studied with molecular dynamics simulations

por Chen, Yu Wai, Kong, Wai-Po, Wong, Kwok-Yin
Publicado 2023

Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL (pro)) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates

por Chen, Yu Wai, Yiu, Chin-Pang Bennu, Wong, Kwok-Yin
Publicado 2020

Virtual screening on the web for drug repurposing: a primer

por Chen, Yu Wai, Yiu, Chin-Pang Bennu, Wong, Kwok-Yin
Publicado 2021

Thermostable β-Lactamase Mutant with Its Active Site Conjugated with Fluorescein for Efficient β-Lactam Antibiotic Detection

por Au, Ho-Wah, Tsang, Man-Wah, So, Pui-Kin, Wong, Kwok-Yin, Leung, Yun-Chung
Publicado 2019

Structural studies of the mechanism for biosensing antibiotics in a fluorescein-labeled β-lactamase

por Wong, Wai-Ting, Au, Ho-Wah, Yap, Hong-Kin, Leung, Yun-Chung, Wong, Kwok-Yin, Zhao, Yanxiang
Publicado 2011

Effect of Lactamase Inhibitors on the Biosensor Penp during the Measurement of Lactam Antibiotics Concentration

por Soto, Dagoberto, Silva, Camila, Ugalde, Cristian, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Andresen, Max
Publicado 2019

Specific Amino Acid Substitutions in OXA-51-Type β-Lactamase Enhance Catalytic Activity to a Level Comparable to Carbapenemase OXA-23 and OXA-24/40

por Chan, Kwan-Wai, Liu, Chen-Yu, Wong, Ho-Yin, Chan, Wai-Chi, Wong, Kwok-Yin, Chen, Sheng
Publicado 2022

Functional and phylogenetic analysis of TetX variants to design a new classification system

por Cheng, Qipeng, Cheung, Yanchu, Liu, Chenyu, Chan, Edward Wai Chi, Wong, Kwok Yin, Zhang, Rong, Chen, Sheng
Publicado 2022

Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy

por Sepúlveda, Rodrigo A., Downey, Patricio, Soto, Dagoberto, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Andresen, Max
Publicado 2019

BADAN-conjugated β-lactamases as biosensors for β-lactam antibiotic detection

por Au, Ho-Wah, Tsang, Man-Wah, Chen, Yu Wai, So, Pui-Kin, Wong, Kwok-Yin, Leung, Yun-Chung
Publicado 2020

Gossypol acetate: A natural polyphenol derivative with antimicrobial activities against the essential cell division protein FtsZ

por Du, Ruo-Lan, Chow, Ho-Yin, Chen, Yu Wei, Chan, Pak-Ho, Daniel, Richard A., Wong, Kwok-Yin
Publicado 2023

pH-dependent and cathepsin B activable CaCO(3) nanoprobe for targeted in vivo tumor imaging

por Sun, Ning, Wang, Dou, Yao, Guoqiang, Li, Xiaomei, Mei, Ting, Zhou, Xinke, Wong, Kwok-Yin, Jiang, Baishan, Fang, Zhiyuan
Publicado 2019

The structural dynamics of full-length divisome transmembrane proteins FtsQ, FtsB, and FtsL in FtsQBL complex formation

por Kong, Wai-Po, Gong, Furong, So, Pui-Kin, Chen, Yu Wai, Chan, Pak-Ho, Leung, Yun-Chung, Wong, Kwok-Yin
Publicado 2022

Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris

por Law, Kin-Ho, Tsang, Man-Wah, Wong, Yuk-Ki, Tsang, Ming-San, Lau, Pui-Yee, Wong, Kwok-Yin, Ho, Kwok-Ping, Leung, Yun-Chung
Publicado 2018

Rational structural modification of the isatin scaffold to develop new and potent antimicrobial agents targeting bacterial peptidoglycan glycosyltransferase

por Wang, Yong, Liang, Zhiguang, Zheng, Yuanyuan, Leung, Alan Siu-Lun, Yan, Siu-Cheong, So, Pui-Kin, Leung, Yun-Chung, Wong, Wing-Leung, Wong, Kwok-Yin
Publicado 2021

Antibacterial activity and mechanism of action of a thiophenyl substituted pyrimidine derivative

por Fang, Zhiyuan, Li, Yanan, Zheng, Yuanyuan, Li, Xiaomei, Lu, Yu-Jing, Yan, Siu-Cheong, Wong, Wing-Leung, Chan, Kin-Fai, Wong, Kwok-yin, Sun, Ning
Publicado 2019

An antibacterial platform based on capacitive carbon-doped TiO(2) nanotubes after direct or alternating current charging

por Wang, Guomin, Feng, Hongqing, Hu, Liangsheng, Jin, Weihong, Hao, Qi, Gao, Ang, Peng, Xiang, Li, Wan, Wong, Kwok-Yin, Wang, Huaiyu, Li, Zhou, Chu, Paul K.
Publicado 2018

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lac...

por Andresen, Max, Araos, Joaquin, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Wong, Wai-Ting, Cabrera, Salvador, Silva, Camila, Alegria, Leyla, Bruhn, Alejandro, Soto, Dagoberto
Publicado 2018

Method Based on the β-Lactamase PenPC Fluorescent Labeled for β-Lactam Antibiotic Quantification in Human Plasma

por Andresen, Max, Wong, Kwok-Yin, Leung, Yun-Chung, Wong, Wai-Ting, Chan, Pak-Ho, Andresen-Vasquez, Max, Alegria, Leyla, Silva, Camila, Tapia, Pablo, Downey, Patricio, Soto, Dagoberto
Publicado 2016

Study of Benzofuroquinolinium Derivatives as a New Class of Potent Antibacterial Agent and the Mode of Inhibition Targeting FtsZ

por Zheng, Yuan-Yuan, Du, Ruo-Lan, Cai, Sen-Yuan, Liu, Zhi-Hua, Fang, Zhi-Yuan, Liu, Ting, So, Lok-Yan, Lu, Yu-Jing, Sun, Ning, Wong, Kwok-Yin
Publicado 2018