A Simple Cloning-free Method to Efficiently Induce Gene Expression Using CRISPR/Cas9

por Fang, Lyujie, Hung, Sandy S.C., Yek, Jennifer, El Wazan, Layal, Nguyen, Tu, Khan, Shahnaz, Lim, Shiang Y., Hewitt, Alex W., Wong, Raymond C.B.
Publicado 2018

Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

por Hung, Sandy S.C., Van Bergen, Nicole J., Jackson, Stacey, Liang, Helena, Mackey, David A., Hernández, Damián, Lim, Shiang Y., Hewitt, Alex W., Trounce, Ian, Pébay, Alice, Wong, Raymond C.B.
Publicado 2016

Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant

por Tran, Minh Thuan Nguyen, Khalid, Mohd Khairul Nizam Mohd, Pébay, Alice, Cook, Anthony L., Liang, Helena H., Wong, Raymond C.B., Craig, Jamie E., Liu, Guei-Sheung, Hung, Sandy S., Hewitt, Alex W.
Publicado 2019

Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

por Nguyen, Tu, Urrutia-Cabrera, Daniel, Wang, Luozixian, Lees, Jarmon G., Wang, Jiang-Hui, Hung, Sandy S.C., Hewitt, Alex W., Edwards, Thomas L., McLenachan, Sam, Chen, Fred K., Lim, Shiang Y., Luu, Chi D., Guymer, Robyn, Wong, Raymond C.B.
Publicado 2023

Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy

por Wong, Raymond C.B., Lim, Shiang Y., Hung, Sandy S.C., Jackson, Stacey, Khan, Shahnaz, Van Bergen, Nicole J., De Smit, Elisabeth, Liang, Helena H., Kearns, Lisa S, Clarke, Linda, Mackey, David A., Hewitt, Alex W., Trounce, Ian A., Pébay, Alice
Publicado 2017

Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency

por Crombie, Duncan E., Curl, Claire L., Raaijmakers, Antonia JA, Sivakumaran, Priyadharshini, Kulkarni, Tejal, Wong, Raymond CB, Minami, Itsunari, Evans-Galea, Marguerite V., Lim, Shiang Y., Delbridge, Lea, Corben, Louise A., Dottori, Mirella, Nakatsuji, Norio, Trounce, Ian A., Hewitt, Alex W., Delatycki, Martin B., Pera, Martin F., Pébay, Alice
Publicado 2017