Selective Signal Capture from Multidimensional GPCR Outputs with Biased Agonists: Progress Towards Novel Drug Development

por Kim, Donghwa, Tokmakova, Alina, Woo, Jung-A A., An, Steven S., Goddard, William A., Liggett, Stephen B.
Publicado 2022

Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics

por Cazzaro, Sara, Fang, Cenxiao, Khan, Hirah, Witas, Richard, Kee, Teresa R., Woo, Jung-A. A., Kang, David E.
Publicado 2022

Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation

por Liu, Tian, Wang, Fang, LePochat, Patrick, Woo, Jung-A. A., Bukhari, Mohammed Zaheen, Hong, Kyung Woo, Trotter, Courtney, Kang, David E.
Publicado 2017

A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14

por Woo, Jung-A A., Castaño, Maria, Kee, Teresa R., Lee, Jordan, Koziol-White, Cynthia J., An, Steven S., Kim, Donghwa, Kang, David E., Liggett, Stephen B.
Publicado 2023

SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation

por Fang, Cenxiao, Woo, Jung-A A., Liu, Tian, Zhao, Xingyu, Cazzaro, Sara, Yan, Yan, Matlack, Jenet, Kee, Teresa, LePochat, Patrick, Kang, David E.
Publicado 2020

Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models

por Kee, Teresa R., Espinoza Gonzalez, Pamela, Wehinger, Jessica L., Bukhari, Mohammed Zaheen, Ermekbaeva, Aizara, Sista, Apoorva, Kotsiviras, Peter, Liu, Tian, Kang, David E., Woo, Jung-A. A.
Publicado 2021

Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics

por Woo, Jung-A. A., Liu, Tian, Fang, Cenxiao C., Cazzaro, Sara, Kee, Teresa, LePochat, Patrick, Yrigoin, Ksenia, Penn, Courtney, Zhao, Xingyu, Wang, Xinming, Liggett, Stephen B., Kang, David E.
Publicado 2019

Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity

por Woo, Jung-A. A., Liu, Tian, Trotter, Courtney, Fang, Cenxiao C., De Narvaez, Emillio, LePochat, Patrick, Maslar, Drew, Bukhari, Anusha, Zhao, Xingyu, Deonarine, Andrew, Westerheide, Sandy D., Kang, David E.
Publicado 2017

Identification and characterization of an atypical Gαs-biased β(2)AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis

por Kim, Donghwa, Tokmakova, Alina, Lujan, Lauren K., Strzelinski, Hannah R., Kim, Nicholas, Najari Beidokhti, Maliheh, Giulianotti, Marc A., Mafi, Amirhossein, Woo, Jung-A A., An, Steven S., Goddard, William A., Liggett, Stephen B.
Publicado 2021

Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10

por Liu, Tian, Woo, Jung-A. A., Bukhari, Mohammed Zaheen, Wang, Xinming, Yan, Yan, Buosi, Sara Cazzaro, Ermekbaeva, Aizara, Sista, Apoorva, Kotsiviras, Peter, LePochat, Patrick, Chacko, Ann, Zhao, Xingyu, Kang, David E.
Publicado 2022

Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation

por Kee, Teresa R, Wehinger, Jessica L, Gonzalez, Pamela Espinoza, Nguyen, Eric, McGill Percy, Kyle C, Khan, Sophia A, Chaput, Dale, Wang, Xinming, Liu, Tian, Kang, David E, Woo, Jung-A A
Publicado 2022