Comparison of the Hepatotoxic Potential of Two Treatments for Autosomal-Dominant Polycystic Kidney DiseaseUsing Quantitative Systems Toxicology Modeling

por Woodhead, J. L., Pellegrini, L., Shoda, L. K. M., Howell, B. A.
Publicado 2020

MITOsym®: A Mechanistic, Mathematical Model of Hepatocellular Respiration and Bioenergetics

por Yang, Y., Nadanaciva, S., Will, Y., Woodhead, J. L., Howell, B. A., Watkins, P. B., Siler, S. Q.
Publicado 2014

A Mechanistic Model of Drug-Induced Liver Injury Aids the Interpretation of Elevated Liver Transaminase Levels in a Phase I Clinical Trial

por Howell, B A, Siler, S Q, Shoda, L K M, Yang, Y, Woodhead, J L, Watkins, P B
Publicado 2014

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid–Mediated DILI

por Woodhead, J L, Yang, K, Brouwer, K L R, Siler, S Q, Stahl, S H, Ambroso, J L, Baker, D, Watkins, P B, Howell, B A
Publicado 2014