A Commentary On: “NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease”. A cautionary note regarding...

por Woodruff, Trent M., Tenner, Andrea J.
Publicado 2015

Commentary: Beyond C4: Analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls

por Coulthard, Liam G., Woodruff, Trent M.
Publicado 2019

The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics

por Woodruff, Trent M., Shukla, Arun K.
Publicado 2020

Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the do...

por Khan, Nemat, Gordon, Richard, Woodruff, Trent M, Smith, Maree T
Publicado 2015

Serping1/C1 Inhibitor Affects Cortical Development in a Cell Autonomous and Non-cell Autonomous Manner

por Gorelik, Anna, Sapir, Tamar, Woodruff, Trent M., Reiner, Orly
Publicado 2017

Development and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice

por Kumar, Vinod, Lee, John D., Clark, Richard J., Woodruff, Trent M.
Publicado 2018

The Receptor for Advanced Glycation Endproducts Does Not Contribute to Pathology in a Mouse Mesenteric Ischemia/Reperfusion-Induced Injury Model

por Wu, Mike C. L., Gilmour, Timothy D., Mantovani, Susanna, Woodruff, Trent M.
Publicado 2015

The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain

por Warwick, Charles A., Keyes, Alex L., Woodruff, Trent M., Usachev, Yuriy M.
Publicado 2021

Valproic acid attenuates cellular senescence in diabetic kidney disease through the inhibition of complement C5a receptors

por Coughlan, Melinda T., Ziemann, Mark, Laskowski, Adrienne, Woodruff, Trent M., Tan, Sih Min
Publicado 2022

The Peripheral Immune System and Amyotrophic Lateral Sclerosis

por McCombe, Pamela A., Lee, John D., Woodruff, Trent M., Henderson, Robert D.
Publicado 2020

Complement Component 5 (C5) Deficiency Improves Cognitive Outcome After Traumatic Brain Injury and Enhances Treatment Effects of Complement Inhibitors C1-Inh and CR2-Crry in a Mous...

por Chen, Min, Edwards, Stephen R., Maskey, Dhiraj, Woodruff, Trent M., Tomlinson, Stephen, Reutens, David
Publicado 2023

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis

por Lee, Jia Y, Lee, John D, Phipps, Simon, Noakes, Peter G, Woodruff, Trent M
Publicado 2015

Developmental activities of the complement pathway in migrating neurons

por Gorelik, Anna, Sapir, Tamar, Haffner-Krausz, Rebecca, Olender, Tsviya, Woodruff, Trent M., Reiner, Orly
Publicado 2017

Editorial: The Role of Complement in Tumors

por Rolfe, Barbara E., Pio, Ruben, Woodruff, Trent M., Markiewski, Maciej M., Manthey, Helga D.
Publicado 2020

Chemical synthesis and characterisation of the complement C5 inhibitory peptide zilucoplan

por Gorman, Declan M., Lee, John, Payne, Colton D., Woodruff, Trent M., Clark, Richard J.
Publicado 2021

The “C3aR Antagonist” SB290157 is a Partial C5aR2 Agonist

por Li, Xaria X., Kumar, Vinod, Clark, Richard J., Lee, John D., Woodruff, Trent M.
Publicado 2021

TLQP-21 is a low potency partial C3aR activator on human primary macrophages

por Li, Xaria X., Lee, John D., Lee, Han S., Clark, Richard J., Woodruff, Trent M.
Publicado 2023

Complement activation in the injured central nervous system: another dual-edged sword?

por Brennan, Faith H, Anderson, Aileen J, Taylor, Stephen M, Woodruff, Trent M, Ruitenberg, Marc J
Publicado 2012

Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking

por Tamamis, Phanourios, Kieslich, Chris A, Nikiforovich, Gregory V, Woodruff, Trent M, Morikis, Dimitrios, Archontis, Georgios
Publicado 2014

Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis

por Wang, Haitao A., Lee, John D., Lee, Kah Meng, Woodruff, Trent M., Noakes, Peter G.
Publicado 2017