Conformational and thermodynamic hallmarks of DNA operator site specificity in the copper sensitive operon repressor from Streptomyces lividans

por Tan, Benedict G., Vijgenboom, Erik, Worrall, Jonathan A. R.
Publicado 2014

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

por Hough, Michael A., Prischi, Filippo, Worrall, Jonathan A. R.
Publicado 2023

New insights into controlling radical migration pathways in heme enzymes gained from the study of a dye-decolorising peroxidase

por Lučić, Marina, Wilson, Michael T., Pullin, Jacob, Hough, Michael A., Svistunenko, Dimitri A., Worrall, Jonathan A. R.
Publicado 2023

Morphological development and cytochrome c oxidase activity in Streptomyces lividans are dependent on the action of a copper bound Sco protein

por Blundell, Katie L. I. M., Wilson, Michael T., Svistunenko, Dimitri A., Vijgenboom, Erik, Worrall, Jonathan A. R.
Publicado 2013

Allosteric Activation of the ATPase Activity of the Escherichia coli RhlB RNA Helicase*

por Worrall, Jonathan A. R., Howe, Françoise S., McKay, Adam R., Robinson, Carol V., Luisi, Ben F.
Publicado 2008

Aspartate or arginine? Validated redox state X-ray structures elucidate mechanistic subtleties of Fe(IV) = O formation in bacterial dye-decolorizing peroxidases

por Lučić, Marina, Wilson, Michael T., Svistunenko, Dimitri A., Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Publicado 2021

The DyP-type peroxidase DtpA is a Tat-substrate required for GlxA maturation and morphogenesis in Streptomyces

por Petrus, Marloes L. C., Vijgenboom, Erik, Chaplin, Amanda K., Worrall, Jonathan A. R., van Wezel, Gilles P., Claessen, Dennis
Publicado 2016

Using cryo-EM to understand antimycobacterial resistance in the catalase-peroxidase (KatG) from Mycobacterium tuberculosis

por Munir, Asma, Wilson, Michael T., Hardwick, Steven W., Chirgadze, Dimitri Y., Worrall, Jonathan A.R., Blundell, Tom L., Chaplin, Amanda K.
Publicado 2021

Increased dynamics in the 40–57 Ω-loop of the G41S variant of human cytochrome c promote its pro-apoptotic conformation

por Karsisiotis, Andreas Ioannis, Deacon, Oliver M., Wilson, Michael T., Macdonald, Colin, Blumenschein, Tharin M. A., Moore, Geoffrey R., Worrall, Jonathan A. R.
Publicado 2016

Serial Femtosecond Crystallography Reveals the Role of Water in the One- or Two-Electron Redox Chemistry of Compound I in the Catalytic Cycle of the B-Type Dye-Decolorizing Peroxid...

por Lučić, Marina, Wilson, Michael T., Tosha, Takehiko, Sugimoto, Hiroshi, Shilova, Anastasya, Axford, Danny, Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Publicado 2022

Photoreduction and validation of haem–ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction

por Kekilli, Demet, Moreno-Chicano, Tadeo, Chaplin, Amanda K., Horrell, Sam, Dworkowski, Florian S. N., Worrall, Jonathan A. R., Strange, Richard W., Hough, Michael A.
Publicado 2017

Iron Oxidation in Escherichia coli Bacterioferritin Ferroxidase Centre, a Site Designed to React Rapidly with H(2)O(2) but Slowly with O(2)

por Pullin, Jacob, Wilson, Michael T., Clémancey, Martin, Blondin, Geneviève, Bradley, Justin M., Moore, Geoffrey R., Le Brun, Nick E., Lučić, Marina, Worrall, Jonathan A. R., Svistunenko, Dimitri A.
Publicado 2021

Successful sample preparation for serial crystallography experiments

por Beale, John H., Bolton, Rachel, Marshall, Stephen A., Beale, Emma V., Carr, Stephen B., Ebrahim, Ali, Moreno-Chicano, Tadeo, Hough, Michael A., Worrall, Jonathan A. R., Tews, Ivo, Owen, Robin L.
Publicado 2019

Serial Femtosecond Zero Dose Crystallography Captures a Water‐Free Distal Heme Site in a Dye‐Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe(IV)=O Formatio...

por Lučić, Marina, Svistunenko, Dimitri A., Wilson, Michael T., Chaplin, Amanda K., Davy, Bradley, Ebrahim, Ali, Axford, Danny, Tosha, Takehiko, Sugimoto, Hiroshi, Owada, Shigeki, Dworkowski, Florian S. N., Tews, Ivo, Owen, Robin L., Hough, Michael A., Worrall, Jonathan A. R.
Publicado 2020

Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins

por Ebrahim, Ali, Moreno-Chicano, Tadeo, Appleby, Martin V., Chaplin, Amanda K., Beale, John H., Sherrell, Darren A., Duyvesteyn, Helen M. E., Owada, Shigeki, Tono, Kensuke, Sugimoto, Hiroshi, Strange, Richard W., Worrall, Jonathan A. R., Axford, Danny, Owen, Robin L., Hough, Michael A.
Publicado 2019

High-throughput structures of protein–ligand complexes at room temperature using serial femtosecond crystallography

por Moreno-Chicano, Tadeo, Ebrahim, Ali, Axford, Danny, Appleby, Martin V., Beale, John H., Chaplin, Amanda K., Duyvesteyn, Helen M. E., Ghiladi, Reza A., Owada, Shigeki, Sherrell, Darren A., Strange, Richard W., Sugimoto, Hiroshi, Tono, Kensuke, Worrall, Jonathan A. R., Owen, Robin L., Hough, Michael A.
Publicado 2019

Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature

por Moreno-Chicano, Tadeo, Carey, Leiah M., Axford, Danny, Beale, John H., Doak, R. Bruce, Duyvesteyn, Helen M. E., Ebrahim, Ali, Henning, Robert W., Monteiro, Diana C. F., Myles, Dean A., Owada, Shigeki, Sherrell, Darren A., Straw, Megan L., Šrajer, Vukica, Sugimoto, Hiroshi, Tono, Kensuke, Tosha, Takehiko, Tews, Ivo, Trebbin, Martin, Strange, Richard W., Weiss, Kevin L., Worrall, Jonathan A. R., Meilleur, Flora, Owen, Robin L., Ghiladi, Reza A., Hough, Michael A.
Publicado 2022