Crystallization and X-ray data analysis of the 10 kDa C-terminal lid subdomain from Caenorhabditis elegans Hsp70

por Worrall, Liam, Walkinshaw, Malcolm D.
Publicado 2006

Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling

por Workman, Sean D., Worrall, Liam J., Strynadka, Natalie C. J.
Publicado 2018

Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry

por Majewski, Dorothy D., Worrall, Liam J., Hong, Chuan, Atkinson, Claire E., Vuckovic, Marija, Watanabe, Nobuhiko, Yu, Zhiheng, Strynadka, Natalie C. J.
Publicado 2019

X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation

por Lee, Jaeyong, Kenward, Calem, Worrall, Liam J., Vuckovic, Marija, Gentile, Francesco, Ton, Anh-Tien, Ng, Myles, Cherkasov, Artem, Strynadka, Natalie C. J., Paetzel, Mark
Publicado 2022

X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid

por Lizak, Christian, Worrall, Liam J., Baumann, Lars, Pfleiderer, Moritz M., Volkers, Gesa, Sun, Tianjun, Sim, Lyann, Wakarchuk, Warren, Withers, Stephen G., Strynadka, Natalie C. J.
Publicado 2017

Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli

por Caveney, Nathanael A., Caballero, Guillermo, Voedts, Henri, Niciforovic, Ana, Worrall, Liam J., Vuckovic, Marija, Fonvielle, Matthieu, Hugonnet, Jean-Emmanuel, Arthur, Michel, Strynadka, Natalie C. J.
Publicado 2019

Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance

por Sobhanifar, Solmaz, Worrall, Liam J., King, Dustin T., Wasney, Gregory A., Baumann, Lars, Gale, Robert T., Nosella, Michael, Brown, Eric D., Withers, Stephen G., Strynadka, Natalie C. J.
Publicado 2016

Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site

por Lee, Jaeyong, Worrall, Liam J., Vuckovic, Marija, Rosell, Federico I., Gentile, Francesco, Ton, Anh-Tien, Caveney, Nathanael A., Ban, Fuqiang, Cherkasov, Artem, Paetzel, Mark, Strynadka, Natalie C. J.
Publicado 2020

A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly

por Bergeron, Julien R. C., Worrall, Liam J., Sgourakis, Nikolaos G., DiMaio, Frank, Pfuetzner, Richard A., Felise, Heather B., Vuckovic, Marija, Yu, Angel C., Miller, Samuel I., Baker, David, Strynadka, Natalie C. J.
Publicado 2013

Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus

por Alexander, J. Andrew N., Worrall, Liam J., Hu, Jinhong, Vuckovic, Marija, Satishkumar, Nidhi, Poon, Raymond, Sobhanifar, Solmaz, Rosell, Federico I., Jenkins, Joshua, Chiang, Daniel, Mosimann, Wesley A., Chambers, Henry F., Paetzel, Mark, Chatterjee, Som S., Strynadka, Natalie C. J.
Publicado 2023

Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1

por Mulligan, Vikram Khipple, Workman, Sean, Sun, Tianjun, Rettie, Stephen, Li, Xinting, Worrall, Liam J., Craven, Timothy W., King, Dustin T., Hosseinzadeh, Parisa, Watkins, Andrew M., Renfrew, P. Douglas, Guffy, Sharon, Labonte, Jason W., Moretti, Rocco, Bonneau, Richard, Strynadka, Natalie C. J., Baker, David
Publicado 2021

A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants

por Pérez-Vargas, Jimena, Worrall, Liam J., Olmstead, Andrea D., Ton, Anh-Tien, Lee, Jaeyong, Villanueva, Ivan, Thompson, Connor A. H., Dudek, Svenja, Ennis, Siobhan, Smith, Jason R., Shapira, Tirosh, De Guzman, Joshua, Gang, Shutong, Ban, Fuqiang, Vuckovic, Marija, Bielecki, Michael, Kovacic, Suzana, Kenward, Calem, Hong, Christopher Yee, Gordon, Danielle G., Levett, Paul N., Krajden, Mel, Leduc, Richard, Boudreault, Pierre-Luc, Niikura, Masahiro, Paetzel, Mark, Young, Robert N., Cherkasov, Artem, Strynadka, Natalie C. J., Jean, François
Publicado 2023

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity

por Weisser, Nina E., Sanches, Mario, Escobar-Cabrera, Eric, O’Toole, Jason, Whalen, Elizabeth, Chan, Peter W. Y., Wickman, Grant, Abraham, Libin, Choi, Kate, Harbourne, Bryant, Samiotakis, Antonios, Rojas, Andrea Hernández, Volkers, Gesa, Wong, Jodi, Atkinson, Claire E., Baardsnes, Jason, Worrall, Liam J., Browman, Duncan, Smith, Emma E., Baichoo, Priya, Cheng, Chi Wing, Guedia, Joy, Kang, Sohyeong, Mukhopadhyay, Abhishek, Newhook, Lisa, Ohrn, Anders, Raghunatha, Prajwal, Zago-Schmitt, Matteo, Schrag, Joseph D., Smith, Joel, Zwierzchowski, Patricia, Scurll, Joshua M., Fung, Vincent, Black, Sonia, Strynadka, Natalie C. J., Gold, Michael R., Presta, Leonard G., Ng, Gordon, Dixit, Surjit
Publicado 2023