Computational modelling for the sustainable management of chemicals

por Worth, Andrew P.
Publicado 2020

Towards a future regulatory framework for chemicals in the European Union – Chemicals 2.0

por Berggren, Elisabet, Worth, Andrew P.
Publicado 2023

Canine Degenerative Lumbosacral Stenosis: Prevalence, Impact And Management Strategies

por Worth, Andrew, Meij, Björn, Jeffery, Nicholas
Publicado 2019

Dedication to Dr J.M. Zaldívar Comenges (1958–2012)

por Whelan, Maurice, Worth, Andrew, Coecke, Sandra, Blaauboer, Bas
Publicado 2017

Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment

por Madia, Federica, Worth, Andrew, Whelan, Maurice, Corvi, Raffaella
Publicado 2019

Editorial: Advances and Refinements in the Development and Application of Threshold of Toxicological Concern

por Patlewicz, Grace, Worth, Andrew, Yang, Chihae, Zhu, Tingting
Publicado 2022

Optimising testing strategies for classification of human health and environmental hazards – A proof-of-concept study

por Da Silva, Emilie, Baun, Anders, Berggren, Elisabet, Worth, Andrew
Publicado 2020

The role of validation in establishing the scientific credibility of predictive toxicology approaches intended for regulatory application

por Patterson, Eann A., Whelan, Maurice P., Worth, Andrew P.
Publicado 2021

Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort

por Paini, Alicia, Tan, Yu-Mei, Sachana, Magdalini, Worth, Andrew
Publicado 2021

The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data – A case study with caffeine

por Bessems, Jos G.M., Paini, Alicia, Gajewska, Monika, Worth, Andrew
Publicado 2017

Application of new statistical distribution approaches for environmental mixture risk assessment: A case study

por Kienzler, Aude, Bopp, Stephanie, Halder, Marlies, Embry, Michelle, Worth, Andrew
Publicado 2019

Assessment of the predictive capacity of a physiologically based kinetic model using a read-across approach

por Paini, Alicia, Worth, Andrew, Kulkarni, Sunil, Ebbrell, David, Madden, Judith
Publicado 2021

Integration of data across toxicity endpoints for improved safety assessment of chemicals: the example of carcinogenicity assessment

por Madia, Federica, Pillo, Gelsomina, Worth, Andrew, Corvi, Raffaella, Prieto, Pilar
Publicado 2021

Translatability and transferability of in silico models: Context of use switching to predict the effects of environmental chemicals on the immune system

por Pappalardo, Francesco, Russo, Giulia, Corsini, Emanuela, Paini, Alicia, Worth, Andrew
Publicado 2022

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling

por Paini, Alicia, Sala Benito, Jose Vicente, Bessems, Jos, Worth, Andrew P.
Publicado 2017

Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

por Paini, Alicia, Leonard, Jeremy A., Kliment, Tomas, Tan, Yu-Mei, Worth, Andrew
Publicado 2017

Unlocking the potential of in silico chemical safety assessment – A report on a cross-sector symposium on current opportunities and future challenges

por Cronin, Mark T.D., Madden, Judith C., Yang, Chihae, Worth, Andrew P.
Publicado 2019

Role of Physiologically Based Kinetic modelling in addressing environmental chemical mixtures – A review

por Desalegn, Anteneh, Bopp, Stephanie, Asturiol, David, Lamon, Lara, Worth, Andrew, Paini, Alicia
Publicado 2019

A matter of trust: Learning lessons about causality will make qAOPs credible

por Spînu, Nicoleta, Cronin, Mark T.D., Madden, Judith C., Worth, Andrew P.
Publicado 2022

Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes

por Worth, Andrew P., Louisse, Jochem, Macko, Peter, Sala Benito, J.V., Paini, Alicia
Publicado 2017