Signal integration in TGF-β, WNT, and Hippo pathways

por Attisano, Liliana, Wrana, Jeffrey L.
Publicado 2013

Recent advances in understanding contextual TGFβ signaling

por Ayyaz, Arshad, Attisano, Liliana, Wrana, Jeffrey L
Publicado 2017

Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap

por Labibi, Bita, Bashkurov, Mikhail, Wrana, Jeffrey L., Attisano, Liliana
Publicado 2020

Looking into the Black Box: Insights into the Mechanisms of Somatic Cell Reprogramming

por David, Laurent, Samavarchi-Tehrani, Payman, Golipour, Azadeh, Wrana, Jeffrey L.
Publicado 2011

UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways

por MacNeil, Lesley T., Hardy, W. Rod, Pawson, Tony, Wrana, Jeffrey L., Culotti, Joseph G.
Publicado 2009

A critical role for NF2 and the Hippo pathway in branching morphogenesis

por Reginensi, Antoine, Enderle, Leonie, Gregorieff, Alex, Johnson, Randy L., Wrana, Jeffrey L., McNeill, Helen
Publicado 2016

A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening

por Jeon, Jouhyun, Nim, Satra, Teyra, Joan, Datti, Alessandro, Wrana, Jeffrey L, Sidhu, Sachdev S, Moffat, Jason, Kim, Philip M
Publicado 2014

Overexpression of the Severe Acute Respiratory Syndrome Coronavirus-2 Receptor, Angiotensin-Converting Enzyme 2, in Diabetic Kidney Disease: Implications for Kidney Injury in Novel...

por Gilbert, Richard E., Caldwell, Lauren, Misra, Paraish S., Chan, Kin, Burns, Kevin D., Wrana, Jeffrey L., Yuen, Darren A.
Publicado 2021

Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling

por Gumienny, Tina L., MacNeil, Lesley, Zimmerman, Cole M., Wang, Huang, Chin, Lena, Wrana, Jeffrey L., Padgett, Richard W.
Publicado 2010

A lateral signalling pathway coordinates shape volatility during cell migration

por Zhang, Liang, Luga, Valbona, Armitage, Sarah K., Musiol, Martin, Won, Amy, Yip, Christopher M., Plotnikov, Sergey V., Wrana, Jeffrey L.
Publicado 2016

Inhibition of SREBP1 sensitizes cells to death ligands

por Eberhard, Yanina, Gronda, Marcela, Hurren, Rose, Datti, Alessandro, MacLean, Neil, Ketela, Troy, Moffat, Jason, Wrana, Jeffrey L., Schimmer, Aaron D.
Publicado 2011

Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution

por Li, Jingjing, Liu, Yu, Xin, Xiaofeng, Kim, Taehyung Simon, Cabeza, Eduardo Aguiar, Ren, Jie, Nielsen, Rasmus, Wrana, Jeffrey L., Zhang, Zhaolei
Publicado 2012

YAP establishes epiblast responsiveness to inductive signals for germ cell fate

por Kagiwada, Saya, Aramaki, Shinya, Wu, Guangming, Shin, Borami, Kutejova, Eva, Obridge, David, Adachi, Kenjiro, Wrana, Jeffrey L., Hübner, Karin, Schöler, Hans R.
Publicado 2021

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway

por Miller, Bryan W, Lau, Garnet, Grouios, Chris, Mollica, Emanuela, Barrios-Rodiles, Miriam, Liu, Yongmei, Datti, Alessandro, Morris, Quaid, Wrana, Jeffrey L, Attisano, Liliana
Publicado 2009

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog - dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

por Dey, Abhinav, Robitaille, Mélanie, Remke, Marc, Maier, Caroline, Malhotra, Anshu, Gregorieff, Alex, Wrana, Jeffrey L, Taylor, Michael D, Angers, Stéphane, Kenney, Anna Marie
Publicado 2016

Robust production of uniform human cerebral organoids from pluripotent stem cells

por Sivitilli, Adam A, Gosio, Jessica T, Ghoshal, Bibaswan, Evstratova, Alesya, Trcka, Daniel, Ghiasi, Parisa, Hernandez, J Javier, Beaulieu, Jean Martin, Wrana, Jeffrey L, Attisano, Liliana
Publicado 2020

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

por Fraser, Michael, Livingstone, Julie, Wrana, Jeffrey L., Finelli, Antonio, He, Housheng Hansen, van der Kwast, Theodorus, Zlotta, Alexandre R., Bristow, Robert G., Boutros, Paul C.
Publicado 2021

Pulmonary pericytes regulate lung morphogenesis

por Kato, Katsuhiro, Diéguez-Hurtado, Rodrigo, Park, Do Young, Hong, Seon Pyo, Kato-Azuma, Sakiko, Adams, Susanne, Stehling, Martin, Trappmann, Britta, Wrana, Jeffrey L., Koh, Gou Young, Adams, Ralf H.
Publicado 2018

Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility

por Luo, Yi, Barrios-Rodiles, Miriam, Gupta, Gagan D., Zhang, Ying Y., Ogunjimi, Abiodun A., Bashkurov, Mikhail, Tkach, Johnny M., Underhill, Ainsley Q., Zhang, Liang, Bourmoum, Mohamed, Wrana, Jeffrey L., Pelletier, Laurence
Publicado 2019

An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14

por Alqawlaq, Samih, Livne-Bar, Izhar, Williams, Declan, D'Ercole, Joseph, Leung, Sara W., Chan, Darren, Tuccitto, Alessandra, Datti, Alessandro, Wrana, Jeffrey L., Corbett, Anita H., Schmitt-Ulms, Gerold, Sivak, Jeremy M.
Publicado 2020