Curcumin activation of a bacterial mechanosensitive channel underlies its membrane permeability and adjuvant properties

por Wray, Robin, Iscla, Irene, Blount, Paul
Publicado 2021

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations

por Iscla, Irene, Wray, Robin, Eaton, Christina, Blount, Paul
Publicado 2015

Novel MscL agonists that allow multiple antibiotics cytoplasmic access activate the channel through a common binding site

por Wray, Robin, Wang, Junmei, Iscla, Irene, Blount, Paul
Publicado 2020

In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL

por Wray, Robin, Blount, Paul, Wang, Junmei, Iscla, Irene
Publicado 2022

Activation of a Bacterial Mechanosensitive Channel, MscL, Underlies the Membrane Permeabilization of Dual-Targeting Antibacterial Compounds

por Wray, Robin, Wang, Junmei, Blount, Paul, Iscla, Irene
Publicado 2022

The Effects of Airflow on the Mechanosensitive Channels of Escherichia coli MG1655 and the Impact of Survival Mechanisms Triggered

por Ramirez, Violette I., Wray, Robin, Blount, Paul, King, Maria D.
Publicado 2023

Streptomycin potency is dependent on MscL channel expression

por Iscla, Irene, Wray, Robin, Wei, Shuguang, Posner, Bruce, Blount, Paul
Publicado 2014

S. aureus MscL Is a Pentamer In Vivo but of Variable Stoichiometries In Vitro: Implications for Detergent-Solubilized Membrane Proteins

por Dorwart, Michael R., Wray, Robin, Brautigam, Chad A., Jiang, Youxing, Blount, Paul
Publicado 2010

Improving the Design of a MscL-Based Triggered Nanovalve

por Iscla, Irene, Eaton, Christina, Parker, Juandell, Wray, Robin, Kovács, Zoltán, Blount, Paul
Publicado 2013

Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore

por Wray, Robin, Iscla, Irene, Gao, Ya, Li, Hua, Wang, Junmei, Blount, Paul
Publicado 2016

A new antibiotic with potent activity targets MscL

por Iscla, Irene, Wray, Robin, Blount, Paul, Larkins-Ford, Jonah, Conery, Annie L, Ausubel, Frederick M, Ramu, Soumya, Kavanagh, Angela, Huang, Johnny X, Blaskovich, Mark A, Cooper, Matthew A, Obregon-Henao, Andres, Orme, Ian, Tjandra, Edwin S, Stroeher, Uwe H, Brown, Melissa H, Macardle, Cindy, van Holst, Nick, Ling Tong, Chee, Slattery, Ashley D, Gibson, Christopher T, Raston, Colin L, Boulos, Ramiz A
Publicado 2015