Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias

por Wren, Melissa C., Lashley, Tammaryn, Årstad, Erik, Sander, Kerstin
Publicado 2018

Discriminatory ability of next-generation tau PET tracers for Alzheimer’s disease

por Yap, Steven Y, Frias, Barbara, Wren, Melissa C, Schöll, Michael, Fox, Nick C, Årstad, Erik, Lashley, Tammaryn, Sander, Kerstin
Publicado 2021

Imaging tau pathology in Alzheimer’s disease with positron emission tomography: lessons learned from imaging-neuropathology validation studies

por Moscoso, Alexis, Wren, Melissa C., Lashley, Tammaryn, Arstad, Erik, Murray, Melissa E., Fox, Nick C., Sander, Kerstin, Schöll, Michael
Publicado 2022

Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation

por Liu, Feilin, Morderer, Dmytro, Wren, Melissa C., Vettleson-Trutza, Sara A., Wang, Yanzhe, Rabichow, Benjamin E., Salemi, Michelle R., Phinney, Brett S., Oskarsson, Björn, Dickson, Dennis W., Rossoll, Wilfried
Publicado 2022

Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination

por Wang, Na, Wang, Minghui, Jeevaratnam, Suren, Rosenberg, Cassandra, Ikezu, Tadafumi C., Shue, Francis, Doss, Sydney V., Alnobani, Alla, Martens, Yuka A., Wren, Melissa, Asmann, Yan W., Zhang, Bin, Bu, Guojun, Liu, Chia-Chen
Publicado 2022

Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells

por Wren, Melissa C., Zhao, Jing, Liu, Chia-Chen, Murray, Melissa E., Atagi, Yuka, Davis, Mary D., Fu, Yuan, Okano, Hirotaka J., Ogaki, Kotaro, Strongosky, Audrey J., Tacik, Pawel, Rademakers, Rosa, Ross, Owen A., Dickson, Dennis W., Wszolek, Zbigniew K., Kanekiyo, Takahisa, Bu, Guojun
Publicado 2015

Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy

por Khalil, Bilal, Chhangani, Deepak, Wren, Melissa C., Smith, Courtney L., Lee, Jannifer H., Li, Xingli, Puttinger, Christian, Tsai, Chih-Wei, Fortin, Gael, Morderer, Dmytro, Gao, Junli, Liu, Feilin, Lim, Chun Kim, Chen, Jingjiao, Chou, Ching-Chieh, Croft, Cara L., Gleixner, Amanda M., Donnelly, Christopher J., Golde, Todd E., Petrucelli, Leonard, Oskarsson, Björn, Dickson, Dennis W., Zhang, Ke, Shorter, James, Yoshimura, Shige H., Barmada, Sami J., Rincon-Limas, Diego E., Rossoll, Wilfried
Publicado 2022

Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer’s disease

por Liu, Chia-Chen, Yamazaki, Yu, Heckman, Michael G., Martens, Yuka A., Jia, Lin, Yamazaki, Akari, Diehl, Nancy N., Zhao, Jing, Zhao, Na, DeTure, Michael, Davis, Mary D., Felton, Lindsey M., Qiao, Wenhui, Li, Yonghe, Li, Hongmei, Fu, Yuan, Wang, Na, Wren, Melissa, Aikawa, Tomonori, Holm, Marie-Louise, Oue, Hiroshi, Linares, Cynthia, Allen, Mariet, Carrasquillo, Minerva M., Murray, Melissa E., Petersen, Ronald C., Ertekin-Taner, Nilüfer, Dickson, Dennis W., Kanekiyo, Takahisa, Bu, Guojun
Publicado 2020