Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche

por Bankaitis, Eric D., Bechard, Matthew E., Wright, Christopher V.E.
Publicado 2015

PDX1 Binds and Represses Hepatic Genes to Ensure Robust Pancreatic Commitment in Differentiating Human Embryonic Stem Cells

por Teo, Adrian Kee Keong, Tsuneyoshi, Norihiro, Hoon, Shawn, Tan, Ee Kim, Stanton, Lawrence W., Wright, Christopher V.E., Dunn, N. Ray
Publicado 2015

Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3

por Comer, John D., Pan, Fong Cheng, Willet, Spencer G., Haldipur, Parthiv, Millen, Kathleen J., Wright, Christopher V. E., Kaltschmidt, Julia A.
Publicado 2015

Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

por Larsen, Hjalte List, Martín-Coll, Laura, Nielsen, Alexander Valentin, Wright, Christopher V. E., Trusina, Ala, Kim, Yung Hae, Grapin-Botton, Anne
Publicado 2017

PDX1 in Ducts Is Not Required for Postnatal Formation of β-Cells but Is Necessary for Their Subsequent Maturation

por Guo, Lili, Inada, Akari, Aguayo-Mazzucato, Cristina, Hollister-Lock, Jennifer, Fujitani, Yoshio, Weir, Gordon C., Wright, Christopher V.E., Sharma, Arun, Bonner-Weir, Susan
Publicado 2013

Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells

por Bechard, Matthew E., Bankaitis, Eric D., Hipkens, Susan B., Ustione, Alessandro, Piston, David W., Yang, Yu-Ping, Magnuson, Mark A., Wright, Christopher V.E.
Publicado 2016

Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice

por Kodama, Sota, Nakano, Yasuhiro, Hirata, Koji, Furuyama, Kenichiro, Horiguchi, Masashi, Kuhara, Takeshi, Masui, Toshihiko, Kawaguchi, Michiya, Gannon, Maureen, Wright, Christopher V. E., Uemoto, Shinji, Kawaguchi, Yoshiya
Publicado 2016

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis

por Wen, Hui-Ju, Gao, Shan, Wang, Yin, Ray, Michael, Magnuson, Mark A., Wright, Christopher V.E., Di Magliano, Marina Pasca, Frankel, Timothy L., Crawford, Howard C.
Publicado 2019

Reduction of Ptf1a Gene Dosage Causes Pancreatic Hypoplasia and Diabetes in Mice

por Fukuda, Akihisa, Kawaguchi, Yoshiya, Furuyama, Kenichiro, Kodama, Sota, Horiguchi, Masashi, Kuhara, Takeshi, Kawaguchi, Michiya, Terao, Mami, Doi, Ryuichiro, Wright, Christopher V.E., Hoshino, Mikio, Chiba, Tsutomu, Uemoto, Shinji
Publicado 2008

Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell Niche

por Aoki, Reina, Shoshkes-Carmel, Michal, Gao, Nan, Shin, Soona, May, Catherine L., Golson, Maria L., Zahm, Adam M., Ray, Michael, Wiser, Caroline L., Wright, Christopher V.E., Kaestner, Klaus H.
Publicado 2015

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function

por Spaeth, Jason M., Liu, Jin-Hua, Peters, Daniel, Guo, Min, Osipovich, Anna B., Mohammadi, Fardin, Roy, Nilotpal, Bhushan, Anil, Magnuson, Mark A., Hebrok, Matthias, Wright, Christopher V.E., Stein, Roland
Publicado 2019

A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry

por Zhang, Juliet, Weinrich, Jarret A.P., Russ, Jeffrey B., Comer, John D., Bommareddy, Praveen K., DiCasoli, Richard J., Wright, Christopher V.E., Li, Yuqing, van Roessel, Peter J., Kaltschmidt, Julia A.
Publicado 2017

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

por Wang, Xianming, Sterr, Michael, Ansarullah, Burtscher, Ingo, Böttcher, Anika, Beckenbauer, Julia, Siehler, Johanna, Meitinger, Thomas, Häring, Hans-Ulrich, Staiger, Harald, Cernilogar, Filippo M., Schotta, Gunnar, Irmler, Martin, Beckers, Johannes, Wright, Christopher V.E., Bakhti, Mostafa, Lickert, Heiko
Publicado 2019

Pancreatic Islet-Autonomous Insulin and Smoothened-Mediated Signaling Modulate Identity Changes of Glucagon(+) α-Cells

por Cigliola, Valentina, Ghila, Luiza, Thorel, Fabrizio, van Gurp, Léon, Baronnier, Delphine, Oropeza, Daniel, Gupta, Simone, Miyatsuka, Takeshi, Kaneto, Hideaki, Magnuson, Mark A., Osipovich, Anna B., Sander, Maike, Wright, Christopher V. E., Thomas, Melissa K., Furuyama, Kenichiro, Chera, Simona, Herrera, Pedro L.
Publicado 2018

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

por Wang, Xianming, Sterr, Michael, Burtscher, Ingo, Chen, Shen, Hieronimus, Anja, Machicao, Fausto, Staiger, Harald, Häring, Hans-Ulrich, Lederer, Gabriele, Meitinger, Thomas, Cernilogar, Filippo M., Schotta, Gunnar, Irmler, Martin, Beckers, Johannes, Hrabě de Angelis, Martin, Ray, Michael, Wright, Christopher V.E., Bakhti, Mostafa, Lickert, Heiko
Publicado 2018

PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance

por Roy, Nilotpal, Takeuchi, Kenneth K., Ruggeri, Jeanine M., Bailey, Peter, Chang, David, Li, Joey, Leonhardt, Laura, Puri, Sapna, Hoffman, Megan T., Gao, Shan, Halbrook, Christopher J., Song, Yan, Ljungman, Mats, Malik, Shivani, Wright, Christopher V.E., Dawson, David W., Biankin, Andrew V., Hebrok, Matthias, Crawford, Howard C.
Publicado 2016