Q&A: Antibiotic resistance: where does it come from and what can we do about it?

por Wright, Gerard D
Publicado 2010

Back to the future: a new ‘old’ lead for tuberculosis

por Wright, Gerard D
Publicado 2012

Q&A: Antibiotic resistance: what more do we know and what more can we do?

por Wright, Gerard D
Publicado 2013

Unlocking the potential of natural products in drug discovery

por Wright, Gerard D.
Publicado 2018

Antibiotic resistance: it’s bad, but why isn’t it worse?

por Waglechner, Nicholas, Wright, Gerard D.
Publicado 2017

The antibiotic resistance “mobilome”: searching for the link between environment and clinic

por Perry, Julie A., Wright, Gerard D.
Publicado 2013

Opportunities for Synthetic Biology in Antibiotics: Expanding Glycopeptide Chemical Diversity

por Thaker, Maulik N., Wright, Gerard D.
Publicado 2012

Venturicidin A, A Membrane-active Natural Product Inhibitor of ATP synthase Potentiates Aminoglycoside Antibiotics

por Yarlagadda, Venkateswarlu, Medina, Ricardo, Wright, Gerard D.
Publicado 2020

Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2″)-Ia

por Cox, Georgina, Stogios, Peter J., Savchenko, Alexei, Wright, Gerard D.
Publicado 2015

Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading Microbacterium sp. Strain C448

por Martin-Laurent, Fabrice, Marti, Romain, Waglechner, Nicholas, Wright, Gerard D., Topp, Edward
Publicado 2014

ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin

por Bordeleau, Emily, Stogios, Peter J., Evdokimova, Elena, Koteva, Kalinka, Savchenko, Alexei, Wright, Gerard D.
Publicado 2021

GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery

por Xu, Min, Wang, Wenliang, Waglechner, Nicholas, Culp, Elizabeth J., Guitor, Allison K., Wright, Gerard D.
Publicado 2020

Three-Dimensional Structure and Optimization of the Metallo-β-Lactamase Inhibitor Aspergillomarasmine A

por Koteva, Kalinka, Sychantha, David, Rotondo, Caitlyn M., Hobson, Christian, Britten, James F., Wright, Gerard D.
Publicado 2022

Phylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics

por Xu, Min, Wang, Wenliang, Waglechner, Nicholas, Culp, Elizabeth J., Guitor, Allison K., Wright, Gerard D.
Publicado 2022

Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction

por Chan, Derek C. K., Josts, Inokentijs, Koteva, Kalinka, Wright, Gerard D., Tidow, Henning, Burrows, Lori L.
Publicado 2023

Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn(2+)

por Sychantha, David, Rotondo, Caitlyn M., Tehrani, Kamaleddin H.M.E., Martin, Nathaniel I., Wright, Gerard D.
Publicado 2021

A diverse intrinsic antibiotic resistome from a cave bacterium

por Pawlowski, Andrew C., Wang, Wenliang, Koteva, Kalinka, Barton, Hazel A., McArthur, Andrew G., Wright, Gerard D.
Publicado 2016

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes

por Pawlowski, Andrew C., Stogios, Peter J., Koteva, Kalinka, Skarina, Tatiana, Evdokimova, Elena, Savchenko, Alexei, Wright, Gerard D.
Publicado 2018

Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system

por Gómez-Arrebola, Carmen, Hernandez, Sara B., Culp, Elizabeth J., Wright, Gerard D., Solano, Cristina, Cava, Felipe, Lasa, Iñigo
Publicado 2023

Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant Enterococcus

por Koteva, Kalinka, Xu, Min, Wang, Wenliang, Fiebig-Comyn, Aline A., Cook, Michael A., Coombes, Brian K., Wright, Gerard D.
Publicado 2023