Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization

por AL-Quadeib, Bushra T., Radwan, Mahasen A., Siller, Lidija, Horrocks, Benjamin, Wright, Matthew C.
Publicado 2015

Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats

por Radwan, Mahasen A., AlQuadeib, Bushra T., Šiller, Lidija, Wright, Matthew C., Horrocks, Benjamin
Publicado 2017

Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy

por Douglass, Angela, Wallace, Karen, Koruth, Matthew, Barelle, Caroline, Porter, Andrew J., Wright, Matthew C.
Publicado 2008

Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics

por Marek, Carylyn J, Wallace, Karen, Durward, Elaine, Koruth, Matthew, Leel, Val, Leiper, Lucy J, Wright, Matthew C
Publicado 2009

B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals

por Leitch, Alistair C., Probert, Philip M.E., Shayman, James A., Meyer, Stephanie K., Kass, George E.N., Wright, Matthew C.
Publicado 2017

Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids

por Young, Gregory R., Abdelghany, Tarek M., Leitch, Alistair C., Dunn, Michael P., Blain, Peter G., Lanyon, Clare, Wright, Matthew C.
Publicado 2020

Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression

por Fairhall, Emma A., Charles, Michelle A., Probert, Philip M. E., Wallace, Karen, Gibb, Jennifer, Ravindan, Chandni, Soloman, Martin, Wright, Matthew C.
Publicado 2016

Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes

por Alsaeedi, Fouzeyyah, Wilson, Rachel, Candlish, Charlotte, Ibrahim, Ibrahim, Leitch, Alistair C., Abdelghany, Tarek M., Wilson, Colin, Armstrong, Lyle, Wright, Matthew C.
Publicado 2019

Potential for cardiac toxicity with methylimidazolium ionic liquids

por Abdelghany, Tarek M., Hedya, Shireen A., De Santis, Carol, Abd El-Rahman, Sahar S., Gill, Jason H., Abdelkader, Noha F., Wright, Matthew C.
Publicado 2023

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism

por Probert, Philip M., Palmer, Jeremy M., Alhusainy, Wasma, Amer, Aimen O., Rietjens, Ivonne M.C.M., White, Steven A., Jones, David E., Wright, Matthew C.
Publicado 2016

Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies

por Probert, Philip M. E., Chung, Git W., Cockell, Simon J., Agius, Loranne, Mosesso, Pasquale, White, Steven A., Oakley, Fiona, Brown, Colin D. A., Wright, Matthew C.
Publicado 2014

Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes

por Meyer, Stephanie K., Probert, Philip M. E., Lakey, Anne K., Leitch, Alastair C., Blake, Lynsay I., Jowsey, Paul A., Cooke, Martin P., Blain, Peter G., Wright, Matthew C.
Publicado 2017

A mouse model of Huntington’s disease shows altered ultrastructure of transverse tubules in skeletal muscle fibers

por Romer, Shannon H., Metzger, Sabrina, Peraza, Kristiana, Wright, Matthew C., Jobe, D. Scott, Song, Long-Sheng, Rich, Mark M., Foy, Brent D., Talmadge, Robert J., Voss, Andrew A.
Publicado 2021

The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver

por Leitch, Alistair C., Ibrahim, Ibrahim, Abdelghany, Tarek M., Charlton, Alex, Roper, Clair, Vidler, Dan, Palmer, Jeremy M., Wilson, Colin, Jones, David E., Blain, Peter G., Wright, Matthew C.
Publicado 2021

The PXR is a drug target for chronic inflammatory liver disease()

por Wallace, Karen, Cowie, David E., Konstantinou, Dimitrios K., Hill, Stephen J., Tjelle, Torunn E., Axon, Andrew, Koruth, Matthew, White, Steven A., Carlsen, Harald, Mann, Derek A., Wright, Matthew C.
Publicado 2010

Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

por Wilson, Caroline L., Mann, Jelena, Walsh, Meagan, Perrugoria, Maria J., Oakley, Fiona, Wright, Matthew C., Brignole, Chiara, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Karin, Michael, Mann, Derek A.
Publicado 2014

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation

por Amer, Aimen O., Probert, Philip M., Dunn, Michael, Knight, Margaret, Vallance, Abigail E., Flecknell, Paul A., Oakley, Fiona, Cameron, Iain, White, Steven A., Blain, Peter G., Wright, Matthew C.
Publicado 2015

A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo

por Luli, Saimir, Di Paolo, Daniela, Perri, Patrizia, Brignole, Chiara, Hill, Stephen J., Brown, Helen, Leslie, Jack, Marshall, H.L., Wright, Matthew C., Mann, Derek A., Ponzoni, Mirco, Oakley, Fiona
Publicado 2016

Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse

por Leitch, Alistair C., Abdelghany, Tarek M., Charlton, Alex, Grigalyte, Justina, Oakley, Fiona, Borthwick, Lee A., Reed, Lee, Knox, Amber, Reilly, William J., Agius, Loranne, Blain, Peter G., Wright, Matthew C.
Publicado 2020

Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse

por Meyer, Stephanie K., Probert, Philip M.E., Lakey, Anne F., Axon, Andrew R., Leitch, Alistair C., Williams, Faith M., Jowsey, Paul A., Blain, Peter G., Kass, George E.N., Wright, Matthew C.
Publicado 2017