Organotypic human ex vivo models for coronavirus disease 2019 research and drug development

por Youhanna, Sonia, Wright, Shane C., Lauschke, Volker M.
Publicado 2021

Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling

por Petersen, Julian, Wright, Shane C., Rodríguez, David, Matricon, Pierre, Lahav, Noa, Vromen, Aviv, Friedler, Assaf, Strömqvist, Johan, Wennmalm, Stefan, Carlsson, Jens, Schulte, Gunnar
Publicado 2017

Agonist-induced formation of unproductive receptor-G(12) complexes

por Okashah, Najeah, Wright, Shane C., Kawakami, Kouki, Mathiasen, Signe, Zhou, Joris, Lu, Sumin, Javitch, Jonathan A., Inoue, Asuka, Bouvier, Michel, Lambert, Nevin A.
Publicado 2020

Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G(s)

por Xu, Lu, Chen, Bo, Schihada, Hannes, Wright, Shane C., Turku, Ainoleena, Wu, Yiran, Han, Gye-Won, Kowalski-Jahn, Maria, Kozielewicz, Pawel, Bowin, Carl-Fredrik, Zhang, Xianjun, Li, Chao, Bouvier, Michel, Schulte, Gunnar, Xu, Fei
Publicado 2021

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

por Wright, Shane C., Kozielewicz, Paweł, Kowalski-Jahn, Maria, Petersen, Julian, Bowin, Carl-Fredrik, Slodkowicz, Greg, Marti-Solano, Maria, Rodríguez, David, Hot, Belma, Okashah, Najeah, Strakova, Katerina, Valnohova, Jana, Babu, M. Madan, Lambert, Nevin A., Carlsson, Jens, Schulte, Gunnar
Publicado 2019

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics

por Wright, Shane C., Motso, Aikaterini, Koutsilieri, Stefania, Beusch, Christian M., Sabatier, Pierre, Berghella, Alessandro, Blondel-Tepaz, Élodie, Mangenot, Kimberley, Pittarokoilis, Ioannis, Sismanoglou, Despoina-Christina, Le Gouill, Christian, Olsen, Jesper V., Zubarev, Roman A., Lambert, Nevin A., Hauser, Alexander S., Bouvier, Michel, Lauschke, Volker M.
Publicado 2023