Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats

por Cheng, Yu-Chi, Chiu, Yu-Min, Dai, Zen-Kong, Wu, Bin-Nan
Publicado 2021

Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells

por Chen, I-Shan, Dai, Zen-Kong, Welsh, Donald G, Chen, Ing-Jun, Wu, Bin-Nan
Publicado 2011

Cinaciguat Prevents Postnatal Closure of Ductus Arteriosus by Vasodilation and Anti-remodeling in Neonatal Rats

por Hung, Yu-Chi, Liu, Yi-Ching, Wu, Bin-Nan, Yeh, Jwu-Lai, Hsu, Jong-Hau
Publicado 2021

Pre-germinated brown rice prevents high-fat diet induced hyperglycemia through elevated insulin secretion and glucose metabolism pathway in C57BL/6J strain mice

por Shen, Kuo-Ping, Hao, Chi-Long, Yen, Hsueh-Wei, Chen, Chun-Yen, Wu, Bin-Nan, Lin, Hui-Li
Publicado 2015

Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway

por Wu, Jiunn-Ren, Yeh, Jwu-Lai, Liou, Shu-Fen, Dai, Zen-Kong, Wu, Bin-Nan, Hsu, Jong-Hau
Publicado 2016

Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model

por Chen, Jun-Yih, Chu, Li-Wen, Cheng, Kuang-I, Hsieh, Su-Ling, Juan, Yung-Shun, Wu, Bin-Nan
Publicado 2018

Effects of Trans, Trans-2,4-decadienal on the Ions Currents of Cardiomyocytes: Possible Mechanisms of Arrhythmogenesis Induced by Cooking-oil Fumes

por Jhuo, Shih-Jie, Liu, I-Hsin, Tsai, Wei-Chung, Lee, Kun-Tai, Wu, Bin-Nan, Lai, Wen-Ter
Publicado 2020

KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPARγ and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes

por Liu, Chung-Pin, Chau, Pei-Chun, Chang, Chain-Ting, An, Li-Mei, Yeh, Jwu-Lai, Chen, Ing-Jun, Wu, Bin-Nan
Publicado 2018

Vasculoprotective effects of Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction via the NOXs-ROS-NF-κB pathway in spontaneously hypertensive rats

por Sulistyowati, Erna, Jan, Ren-Long, Liou, Shu-Fen, Chen, Ying-Fu, Wu, Bin-Nan, Hsu, Jong-Hau, Yeh, Jwu-Lai
Publicado 2019

In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis

por Huang, Shang-En, Sulistyowati, Erna, Chao, Yu-Ying, Wu, Bin-Nan, Dai, Zen-Kong, Hsu, Jong-Hau, Yeh, Jwu-Lai
Publicado 2021

The Iridoid Glycoside Loganin Modulates Autophagic Flux Following Chronic Constriction Injury-Induced Neuropathic Pain

por Cheng, Kuang-I, Chang, Yu-Chin, Chu, Li-Wen, Hsieh, Su-Ling, An, Li-Mei, Dai, Zen-Kong, Wu, Bin-Nan
Publicado 2022

Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor Ameliorate Metabolic Disorder and Obesity Induced Cardiomyocyte Injury and Mitochondrial Remodeling

por Jhuo, Shih-Jie, Lin, Yi-Hsiung, Liu, I-Hsin, Lin, Tsung-Hsien, Wu, Bin-Nan, Lee, Kun-Tai, Lai, Wen-Ter
Publicado 2023

The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K(+)-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries

por Dai, Zen-Kong, Liu, Yu-Wei, Hsu, Jong-Hau, Yeh, Jwu-Lai, Chen, Ing-Jun, Wu, Jiunn-Ren, Wu, Bin-Nan
Publicado 2015

Decreased Ambient Oxygen Tension Alters the Expression of Endothelin-1, iNOS and cGMP in Rat Alveolar Macrophages

por Chen, I-Chen, Lin, Yu-Tsai, Huang, Jhy-Shrian, Wu, Bin-Nan, Hsu, Jong-Hau, Tan, Mian-Shin, Dai, Zen-Kong
Publicado 2019

Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation

por Cheng, Yu-Chi, Chu, Li-Wen, Chen, Jun-Yih, Hsieh, Su-Ling, Chang, Yu-Chin, Dai, Zen-Kong, Wu, Bin-Nan
Publicado 2020

BK(Ca) Channel Inhibition by Peripheral Nerve Injury Is Restored by the Xanthine Derivative KMUP-1 in Dorsal Root Ganglia

por Cheng, Kuang-I, Yang, Kan-Ting, Kung, Chien-Lun, Cheng, Yu-Chi, Yeh, Jwu-Lai, Dai, Zen-Kong, Wu, Bin-Nan
Publicado 2021

Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

por Sulistyowati, Erna, Lee, Mei-Yueh, Wu, Lin-Chi, Hsu, Jong-Hau, Dai, Zen-Kong, Wu, Bin-Nan, Lin, Ming-Chung, Yeh, Jwu-Lai
Publicado 2018

KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

por Lee, Meng-Luen, Sulistyowati, Erna, Hsu, Jong-Hau, Huang, Bo-Yau, Dai, Zen-Kong, Wu, Bin-Nan, Chao, Yu-Ying, Yeh, Jwu-Lai
Publicado 2019

A Xanthine-Derivative K(+)-Channel Opener Protects against Serotonin-Induced Cardiomyocyte Hypertrophy via the Modulation of Protein Kinases

por Kuo, Hsuan-Fu, Lai, Yan-Jie, Wu, Jung-Chou, Lee, Kun-Tai, Chu, Chih-Sheng, Chen, Ing-Jun, Wu, Jiunn-Ren, Wu, Bin-Nan
Publicado 2013

Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss

por Kuo, Kung-Kai, Wu, Bin-Nan, Liu, Chung-Pin, Yang, Tzu-Yang, Kao, Li-Pin, Wu, Jiunn-Ren, Lai, Wen-Ter, Chen, Ing-Jun
Publicado 2015