Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair

por Wu, Chia-Lung, Kimmerling, Kelly A., Little, Dianne, Guilak, Farshid
Publicado 2017

Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue, and infrapatellar fad pad: The effects of free fatty acids

por Wu, Chia-Lung, Diekman, Brian O’Callaghan, Jain, Deeptee, Guilak, Farshid
Publicado 2012

Poster 116: Integrated scRNA-seq and spatial transcriptomics analysis uncovers distinct cellular populations and transcriptomes in human hip synovium between patients with femoroac...

por Reuter, John, Fadial, Eloise, Ricciardi, Benjamin, Giordano, Brian, Wu, Chia-Lung, Kulzhanova, Gulzada
Publicado 2023

Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

por Dicks, Amanda, Wu, Chia-Lung, Steward, Nancy, Adkar, Shaunak S., Gersbach, Charles A., Guilak, Farshid
Publicado 2020

Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model

por Kenney, H. Mark, Wu, Chia-Lung, Loiselle, Alayna E., Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M.
Publicado 2022

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

por Tang, Ruhang, Jing, Liufang, Willard, Vincent P., Wu, Chia-lung, Guilak, Farshid, Chen, Jun, Setton, Lori A.
Publicado 2018

Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis

por Wu, Chia-Lung, Dicks, Amanda, Steward, Nancy, Tang, Ruhang, Katz, Dakota B., Choi, Yun-Rak, Guilak, Farshid
Publicado 2021

Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity

por Tang, Ruhang, Harasymowicz, Natalia S., Wu, Chia-Lung, Collins, Kelsey H., Choi, Yun-Rak, Oswald, Sara J., Guilak, Farshid
Publicado 2020

Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function

por Ackerman, Jessica E., Best, Katherine T., Muscat, Samantha N., Pritchett, Elizabeth M., Nichols, Anne E.C., Wu, Chia-Lung, Loiselle, Alayna E.
Publicado 2022

Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis

por Kimmerling, Kelly A., Oswald, Sara J., Huebner, Janet L., Little, Dianne, Kraus, Virginia B., Kang, Jing X., Wu, Chia-Lung, Guilak, Farshid
Publicado 2020

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes

por Dicks, Amanda R, Maksaev, Grigory I, Harissa, Zainab, Savadipour, Alireza, Tang, Ruhang, Steward, Nancy, Liedtke, Wolfgang, Nichols, Colin G, Wu, Chia-Lung, Guilak, Farshid
Publicado 2023

Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis

por O’Conor, Christopher J., Ramalingam, Sendhilnathan, Zelenski, Nicole A., Benefield, Halei C., Rigo, Isaura, Little, Dianne, Wu, Chia-Lung, Chen, Di, Liedtke, Wolfgang, McNulty, Amy L., Guilak, Farshid
Publicado 2016

A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery

por Choi, Yun-Rak, Collins, Kelsey H., Springer, Luke E., Pferdehirt, Lara, Ross, Alison K., Wu, Chia-Lung, Moutos, Franklin T., Harasymowicz, Natalia S., Brunger, Jonathan M., Pham, Christine T. N., Guilak, Farshid
Publicado 2021

Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis

por Kenney, H. Mark, Rangel-Moreno, Javier, Peng, Yue, Chen, Kiana L., Bruno, Jennifer, Embong, Abdul, Pritchett, Elizabeth, Fox, Jeffrey I., Becerril-Villanueva, Enrique, Gamboa-Domínguez, Armando, Quataert, Sally, Muthukrishnan, Gowrishankar, Wood, Ronald W., Korman, Benjamin D., Anolik, Jennifer H., Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M., Wu, Chia-Lung
Publicado 2023