Characteristics and driving mechanisms of species beta diversity in desert plant communities

por Jiang, Lamei, Lv, Guanghui, Gong, Yanming, Li, Yan, Wang, Hengfang, Wu, Deyan
Publicado 2021

Structure-Based Design, Synthesis, Biological Evaluation, and Molecular Docking of Novel PDE10 Inhibitors With Antioxidant Activities

por Li, Jinxuan, Chen, Jing-Yi, Deng, Ya-Lin, Zhou, Qian, Wu, Yinuo, Wu, Deyan, Luo, Hai-Bin
Publicado 2018

Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells

por Qiu, Meiying, Wu, Deyan, Huang, Yi-You, Huang, Yue, Zhou, Qian, Tian, Yijing, Guo, Lei, Gao, Yuqi, Luo, Hai-Bin
Publicado 2021

Nobiletin and its derivatives overcome multidrug resistance (MDR) in cancer: total synthesis and discovery of potent MDR reversal agents

por Feng, Senling, Zhou, Huifang, Wu, Deyan, Zheng, Dechong, Qu, Biao, Liu, Ruiming, Zhang, Chen, Li, Zhe, Xie, Ying, Luo, Hai-Bin
Publicado 2020

Free energy perturbation (FEP)-guided scaffold hopping

por Wu, Deyan, Zheng, Xuehua, Liu, Runduo, Li, Zhe, Jiang, Zan, Zhou, Qian, Huang, Yue, Wu, Xu-Nian, Zhang, Chen, Huang, Yi-You, Luo, Hai-Bin
Publicado 2022

Discovery of highly selective and orally available benzimidazole-based phosphodiesterase 10 inhibitors with improved solubility and pharmacokinetic properties for treatment of pulm...

por Yang, Yuncong, Zhang, Sirui, Zhou, Qian, Zhang, Chen, Gao, Yuqi, Wang, Hao, Li, Zhe, Wu, Deyan, Wu, Yinuo, Huang, Yi-You, Guo, Lei, Luo, Hai-Bin
Publicado 2020

A novel inhibitor of N(6)-methyladenosine demethylase FTO induces mRNA methylation and shows anti-cancer activities

por Xie, Guoyou, Wu, Xu-Nian, Ling, Yuyi, Rui, Yalan, Wu, Deyan, Zhou, Jiawang, Li, Jiexin, Lin, Shuibin, Peng, Qin, Li, Zigang, Wang, Hongsheng, Luo, Hai-Bin
Publicado 2022

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

por Li, Zhe, Li, Xin, Huang, Yi-You, Wu, Yaoxing, Liu, Runduo, Zhou, Lingli, Lin, Yuxi, Wu, Deyan, Zhang, Lei, Liu, Hao, Xu, Ximing, Yu, Kunqian, Zhang, Yuxia, Cui, Jun, Zhan, Chang-Guo, Wang, Xin, Luo, Hai-Bin
Publicado 2020