Bi-Epitope SPR Surfaces: A Solution to Develop Robust Immunoassays

por Peng, Li, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F.
Publicado 2014

Structural characterization of a human Fc fragment engineered for lack of effector functions

por Oganesyan, Vaheh, Gao, Changshou, Shirinian, Lena, Wu, Herren, Dall’Acqua, William F.
Publicado 2008

Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab

por Oganesyan, Vaheh, Peng, Li, Woods, Robert M., Wu, Herren, Dall'Acqua, William F.
Publicado 2015

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

por Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall’Acqua, William F, Damschroder, Melissa M
Publicado 2015

Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-interferon antibody fragment and human interferon α-2A

por Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall’Acqua, William F.
Publicado 2008

Molecular basis for the antagonistic activity of an anti-CXCR4 antibody

por Peng, Li, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall'Acqua, William F.
Publicado 2015

Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production

por Roy, Gargi, Zhang, Shu, Li, Lina, Higham, Eileen, Wu, Herren, Marelli, Marcello, Bowen, Michael A.
Publicado 2017

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

por Wang, Bo, Yang, Chunning, Jin, Xiaofang, Du, Qun, Wu, Herren, Dall’Acqua, William, Mazor, Yariv
Publicado 2019

Characterization and in vitro data of antibody drug conjugates (ADCs) derived from heterotrifunctional linker designed for the site-specific preparation of dual ADCs

por Kumar, Amit, Kinneer, Krista, Masterson, Luke, Ezeadi, Ebele, Howard, Philip, Wu, Herren, Gao, Changshou, Dimasi, Nazzareno
Publicado 2018

Fab-Arm Exchange Combined with Selective Protein A Purification Results in a Platform for Rapid Preparation of Monovalent Bispecific Antibodies Directly from Culture Media

por Steinhardt, James, Wu, Yanli, Fleming, Ryan, Ruddle, Ben T., Patel, Pooja, Wu, Herren, Gao, Changshou, Dimasi, Nazzareno
Publicado 2019

Enhancement of Immune Effector Functions by Modulating IgG’s Intrinsic Affinity for Target Antigen

por Mazor, Yariv, Yang, Chunning, Borrok, M. Jack, Ayriss, Joanne, Aherne, Karen, Wu, Herren, Dall’Acqua, William F.
Publicado 2016

Insights into the molecular basis of a bispecific antibody's target selectivity

por Mazor, Yariv, Hansen, Anna, Yang, Chunning, Chowdhury, Partha S, Wang, Jihong, Stephens, Geoffrey, Wu, Herren, Dall’Acqua, William F
Publicado 2015

Molecular basis for the mechanism of action of an anti-TACE antibody

por Peng, Li, Cook, Kimberly, Xu, Linda, Cheng, Li, Damschroder, Melissa, Gao, Changshou, Wu, Herren, Dall'Acqua, William F.
Publicado 2016

Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence

por Mazor, Yariv, Sachsenmeier, Kris F., Yang, Chunning, Hansen, Anna, Filderman, Jessica, Mulgrew, Kathy, Wu, Herren, Dall’Acqua, William F.
Publicado 2017

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action

por Geoghegan, James C., Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F., Wu, Herren, Dall'Acqua, William F., Damschroder, Melissa M.
Publicado 2016

Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies

por Rajan, Saravanan, Kierny, Michael R., Mercer, Andrew, Wu, Jincheng, Tovchigrechko, Andrey, Wu, Herren, Dall′Acqua, William F., Xiao, Xiaodong, Chowdhury, Partha S.
Publicado 2018

Mechanisms of Neutralization of a Human Anti-α-toxin Antibody

por Oganesyan, Vaheh, Peng, Li, Damschroder, Melissa M., Cheng, Li, Sadowska, Agnieszka, Tkaczyk, Christine, Sellman, Bret R., Wu, Herren, Dall'Acqua, William F.
Publicado 2014

A Novel Dual Expression Platform for High Throughput Functional Screening of Phage Libraries in Product like Format

por Xiao, Xiaodong, Chen, Yan, Mugabe, Sheila, Gao, Changshou, Tkaczyk, Christine, Mazor, Yariv, Pavlik, Peter, Wu, Herren, Dall’Acqua, William, Chowdhury, Partha Sarathi
Publicado 2015

Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding

por Oganesyan, Vaheh, Mazor, Yariv, Yang, Chunning, Cook, Kimberly E., Woods, Robert M., Ferguson, Andrew, Bowen, Michael A., Martin, Tom, Zhu, Jie, Wu, Herren, Dall’Acqua, William F.
Publicado 2015

Generation and Characterization of an IgG4 Monomeric Fc Platform

por Shan, Lu, Colazet, Magali, Rosenthal, Kim L., Yu, Xiang-Qing, Bee, Jared S., Ferguson, Andrew, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Oganesyan, Vaheh
Publicado 2016