Synthetic oxepanoprolinamide iboxamycin is active against Listeria monocytogenes despite the intrinsic resistance mediated by VgaL/Lmo0919 ABCF ATPase

por Brodiazhenko, Tetiana, Turnbull, Kathryn Jane, Wu, Kelvin J Y, Takada, Hiraku, Tresco, Ben I C, Tenson, Tanel, Myers, Andrew G, Hauryliuk, Vasili
Publicado 2022

Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp

por Takada, Hiraku, Mandell, Zachary F, Yakhnin, Helen, Glazyrina, Anastasiya, Chiba, Shinobu, Kurata, Tatsuaki, Wu, Kelvin J Y, Tresco, Ben I C, Myers, Andrew G, Aktinson, Gemma C, Babitzke, Paul, Hauryliuk, Vasili
Publicado 2022

Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion

por Aleksandrova, Elena V., Wu, Kelvin J. Y., Tresco, Ben I. C., Syroegin, Egor A., Killeavy, Erin E., Balasanyants, Samson M., Svetlov, Maxim S., Gregory, Steven T., Atkinson, Gemma C., Myers, Andrew G., Polikanov, Yury S.
Publicado 2023

Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR

por Obana, Nozomu, Takada, Hiraku, Crowe-McAuliffe, Caillan, Iwamoto, Mizuki, Egorov, Artyom A, Wu, Kelvin J Y, Chiba, Shinobu, Murina, Victoriia, Paternoga, Helge, Tresco, Ben I C, Nomura, Nobuhiko, Myers, Andrew G, Atkinson, Gemma C, Wilson, Daniel N, Hauryliuk, Vasili
Publicado 2023

A synthetic antibiotic class overcoming bacterial multidrug resistance

por Mitcheltree, Matthew J., Pisipati, Amarnath, Syroegin, Egor A., Silvestre, Katherine J., Klepacki, Dorota, Mason, Jeremy D., Terwilliger, Daniel W., Testolin, Giambattista, Pote, Aditya R., Wu, Kelvin J. Y., Ladley, Richard Porter, Chatman, Kelly, Mankin, Alexander S., Polikanov, Yury S., Myers, Andrew G.
Publicado 2021