Similar dose-dependence of motor neuron cell death caused by wild type human TDP-43 and mutants with ALS-associated amino acid substitutions

por Wu, Lien-Szu, Cheng, Wei-Cheng, Shen, Che-Kun James
Publicado 2013

Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation

por Chiang, Chien-Hao, Grauffel, Cédric, Wu, Lien-Szu, Kuo, Pan-Hsien, Doudeva, Lyudmila G., Lim, Carmay, Shen, Che-Kun James, Yuan, Hanna S.
Publicado 2016

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

por Wu, Lien-Szu, Cheng, Wei-Cheng, Chen, Chia-Ying, Wu, Ming-Che, Wang, Yi-Chi, Tseng, Yu-Hsiang, Chuang, Trees-Juen, Shen, C.-K. James
Publicado 2019

A robust TDP-43 knock-in mouse model of ALS

por Huang, Shih-Ling, Wu, Lien-Szu, Lee, Min, Chang, Chin-Wen, Cheng, Wei-Cheng, Fang, Yu-Sheng, Chen, Yun-Ru, Cheng, Pei-Lin, Shen, Che-Kun James
Publicado 2020