Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

por Wang, Zhiyong, Goto, Yusuke, Allevato, Michael M., Wu, Victoria H., Saddawi-Konefka, Robert, Gilardi, Mara, Alvarado, Diego, Yung, Bryan S., O’Farrell, Aoife, Molinolo, Alfredo A., Duvvuri, Umamaheswar, Grandis, Jennifer R., Califano, Joseph A., Cohen, Ezra E. W., Gutkind, J. Silvio
Publicado 2021

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

por Wang, Zhiyong, Wu, Victoria H., Allevato, Michael M., Gilardi, Mara, He, Yudou, Luis Callejas-Valera, Juan, Vitale-Cross, Lynn, Martin, Daniel, Amornphimoltham, Panomwat, Mcdermott, James, Yung, Bryan S., Goto, Yusuke, Molinolo, Alfredo A., Sharabi, Andrew B., Cohen, Ezra E. W., Chen, Qianming, Lyons, J. Guy, Alexandrov, Ludmil B., Gutkind, J. Silvio
Publicado 2019

Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC

por Saddawi-Konefka, Robert, O’Farrell, Aoife, Faraji, Farhoud, Clubb, Lauren, Allevato, Michael M., Jensen, Shawn M., Yung, Bryan S., Wang, Zhiyong, Wu, Victoria H., Anang, Nana-Ama, Msari, Riyam Al, Schokrpur, Shiruyeh, Pietryga, Ida Franiak, Molinolo, Alfredo A., Mesirov, Jill P., Simon, Aaron B., Fox, Bernard A., Bui, Jack D., Sharabi, Andrew, Cohen, Ezra E. W., Califano, Joseph A., Gutkind, J. Silvio
Publicado 2022

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

por Pagadala, Meghana, Sears, Timothy J., Wu, Victoria H., Pérez-Guijarro, Eva, Kim, Hyo, Castro, Andrea, Talwar, James V., Gonzalez-Colin, Cristian, Cao, Steven, Schmiedel, Benjamin J., Goudarzi, Shervin, Kirani, Divya, Au, Jessica, Zhang, Tongwu, Landi, Teresa, Salem, Rany M., Morris, Gerald P., Harismendy, Olivier, Patel, Sandip Pravin, Alexandrov, Ludmil B., Mesirov, Jill P., Zanetti, Maurizio, Day, Chi-Ping, Fan, Chun Chieh, Thompson, Wesley K., Merlino, Glenn, Gutkind, J. Silvio, Vijayanand, Pandurangan, Carter, Hannah
Publicado 2023