Tumor Extrinsic Factors Mediate Primary T-DM1 Resistance in HER2-Positive Breast Cancer Cells

por Endo, Yukinori, Wu, Wen Jin
Publicado 2021

Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III

por Shekhar, Arvind Chandra, Wu, Wen-Jin, Chen, Hung-Ta
Publicado 2023

In Silico Methods in Antibody Design

por Zhao, Jun, Nussinov, Ruth, Wu, Wen-Jin, Ma, Buyong
Publicado 2018

Structural Insights into RbmA, a Biofilm Scaffolding Protein of V. Cholerae

por Maestre-Reyna, Manuel, Wu, Wen-Jin, Wang, Andrew H.-J.
Publicado 2013

Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity

por Jiang, Jiangsong, Mohan, Nishant, Endo, Yukinori, Shen, Yi, Wu, Wen Jin
Publicado 2017

Cell proliferation and invasion are regulated differently by EGFR and MRP1 in T-DM1-resistant breast cancer cells

por Endo, Yukinori, Lyon, Sarah, Shen, Yi, Mohan, Nishant, Wu, Wen Jin
Publicado 2019

Trastuzumab Blocks the Receiver Function of HER2 Leading to the Population Shifts of HER2-Containing Homodimers and Heterodimers

por Zhao, Jun, Mohan, Nishant, Nussinov, Ruth, Ma, Buyong, Wu, Wen Jin
Publicado 2021

Atezolizumab Induces Necroptosis and Contributes to Hepatotoxicity of Human Hepatocytes

por Endo, Yukinori, Winarski, Katie L., Sajib, Md Sanaullah, Ju, Anna, Wu, Wen Jin
Publicado 2023

VPS34 regulates TSC1/TSC2 heterodimer to mediate RheB and mTORC1/S6K1 activation and cellular transformation

por Mohan, Nishant, Shen, Yi, Dokmanovic, Milos, Endo, Yukinori, Hirsch, Dianne S., Wu, Wen Jin
Publicado 2016

Payload of T-DM1 binds to cell surface cytoskeleton-associated protein 5 to mediate cytotoxicity of hepatocytes

por Endo, Yukinori, Takeda, Kazuyo, Mohan, Nishant, Shen, Yi, Jiang, Jiangsong, Rotstein, David, Wu, Wen Jin
Publicado 2018

Atezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1(+) triple negative breast cancer cells

por Mohan, Nishant, Hosain, Salman, Zhao, Jun, Shen, Yi, Luo, Xiao, Jiang, Jiangsong, Endo, Yukinori, Wu, Wen Jin
Publicado 2019

Identification of a pharmacological approach to reduce ACE2 expression and development of an in vitro COVID-19 viral entry model

por Endo, Yukinori, Hickerson, Brady T., Ilyushina, Natalia A., Mohan, Nishant, Peng, Hanjing, Takeda, Kazuyo, Donnelly, Raymond P., Wu, Wen Jin
Publicado 2022

A Novel Bispecific Antibody Targeting EGFR and VEGFR2 Is Effective against Triple Negative Breast Cancer via Multiple Mechanisms of Action

por Mohan, Nishant, Luo, Xiao, Shen, Yi, Olson, Zachary, Agrawal, Atul, Endo, Yukinori, Rotstein, David S., Pelosof, Lorraine C., Wu, Wen Jin
Publicado 2021

Trastuzumab Alters the Expression of Genes Essential for Cardiac Function and Induces Ultrastructural Changes of Cardiomyocytes in Mice

por ElZarrad, M. Khair, Mukhopadhyay, Partha, Mohan, Nishant, Hao, Enkui, Dokmanovic, Milos, Hirsch, Dianne S., Shen, Yi, Pacher, Pal, Wu, Wen Jin
Publicado 2013

Correction: Trastuzumab Alters the Expression of Genes Essential for Cardiac Function and Induces Ultrastructural Changes of Cardiomyocytes in Mice

por ElZarrad, M. Khair, Mukhopadhyay, Partha, Mohan, Nishant, Hao, Enkui, Dokmanovic, Milos, Hirsch, Dianne S., Shen, Yi, Pacher, Pal, Wu, Wen Jin
Publicado 2014

Comparative Characterization of Different Molecular Formats of Bispecific Antibodies Targeting EGFR and PD-L1

por Mohan, Nishant, Agrawal, Atul, Shen, Yi, Winarski, Katie L., Endo, Yukinori, Dokmanovic, Milos, Schmiel, Deborah, Zheng, Jiwen, Rotstein, David S., Pelosof, Lorraine C., Wu, Wen Jin
Publicado 2022

Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis

por Jiang, Ingjye, Tsai, Chen-Kun, Chen, Sheng-Chia, Wang, Szu-huan, Amiraslanov, Imamaddin, Chang, Chi-Fon, Wu, Wen-Jin, Tai, Jung-Hsiang, Liaw, Yen-Chywan, Huang, Tai-huang
Publicado 2011

The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus‐like structure

por Chang, Chung-ke, Sue, Shih-Che, Yu, Tsan-hung, Hsieh, Chiu-Min, Tsai, Cheng-Kun, Chiang, Yen-Chieh, Lee, Shin-jye, Hsiao, Hsin-hao, Wu, Wen-Jin, Chang, Chi-Fon, Huang, Tai-huang
Publicado 2005

Vibrio cholerae biofilm scaffolding protein RbmA shows an intrinsic, phosphate‐dependent autoproteolysis activity

por Maestre‐Reyna, Manuel, Huang, Wei‐Cheng, Wu, Wen‐Jin, Singh, Praveen K., Hartmann, Raimo, Wang, Po‐Hsun, Lee, Cheng‐Chung, Hikima, Takaaki, Yamamoto, Masaki, Bessho, Yoshitaka, Drescher, Knut, Tsai, Ming‐Daw, Wang, Andrew H.‐J.
Publicado 2020

Modular organization of SARS coronavirus nucleocapsid protein

por Chang, Chung-ke, Sue, Shih-Che, Yu, Tsan-hung, Hsieh, Chiu-Min, Tsai, Cheng-Kun, Chiang, Yen-Chieh, Lee, Shin-jye, Hsiao, Hsin-hao, Wu, Wen-Jin, Chang, Wei-Lun, Lin, Chun-Hung, Huang, Tai-huang
Publicado 2005