Biology of urothelial tumorigenesis: insights from genetically engineered mice

por Wu, Xue-Ru
Publicado 2009

Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin

por Wang, Xing, Zhang, Fenglin, Wu, Xue-Ru
Publicado 2017

Tumorigenicity of RTK/RAS in urothelium

por Wu, Xue-Ru, Mendelsohn, Cathy, DeGraff, David J.
Publicado 2015

The Epithelium—Molecular Landscaping for an Interactive Barrier

por Chai, Karl, Kitamura, Kenichiro, McCann, Amanda, Wu, Xue-Ru
Publicado 2010

Uromodulin Upregulates TRPV5 by Impairing Caveolin-Mediated Endocytosis

por Wolf, Matthias T.F., Wu, Xue-Ru, Huang, Chou-Long
Publicado 2013

FGFR3b Extracellular Loop Mutation Lacks Tumorigenicity In Vivo but Collaborates with p53/pRB Deficiency to Induce High-grade Papillary Urothelial Carcinoma

por Zhou, Haiping, He, Feng, Mendelsohn, Cathy L., Tang, Moon-shong, Huang, Chuanshu, Wu, Xue-Ru
Publicado 2016

PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein

por Peng, Minggang, Wang, Jingjing, Zhang, Dongyun, Jin, Honglei, Li, Jingxia, Wu, Xue-Ru, Huang, Chuanshu
Publicado 2018

Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia

por Ma, Lijie, Liu, Yan, Landry, Nichole K., El-Achkar, Tarek M., Lieske, John C., Wu, Xue-Ru
Publicado 2017

Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy

por Maydan, Olena, McDade, Paul G., Liu, Yan, Wu, Xue‐Ru, Matsell, Douglas G., Eddy, Allison A.
Publicado 2018

Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli

por Liu, Yan, Mémet, Sylvie, Saban, Ricardo, Kong, Xiangpeng, Aprikian, Pavel, Sokurenko, Evgeni, Sun, Tung-Tien, Wu, Xue-Ru
Publicado 2015

Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis

por Zhou, Haiping, Wang, Xing, Mo, Lan, Liu, Yan, He, Feng, Zhang, Fenglin, Huang, Kuo-How, Wu, Xue-Ru
Publicado 2016

DNMT3A/miR-129-2-5p/Rac1 Is an Effector Pathway for SNHG1 to Drive Stem-Cell-like and Invasive Behaviors of Advanced Bladder Cancer Cells

por Xu, Jiheng, Yang, Rui, Li, Jingxia, Wang, Lidong, Cohen, Mitchell, Simeone, Diane M., Costa, Max, Wu, Xue-Ru
Publicado 2022

Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism

por Liu, Zhongbo, Song, Liankun, Xie, Jun, Wu, Xue-Ru, Gin, Greg E., Wang, Beverly, Uchio, Edward, Zi, Xiaolin
Publicado 2023

Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100)

por Xu, Jiawei, Wang, Yulei, Hua, Xiaohui, Xu, Jiheng, Tian, Zhongxian, Jin, Honglei, Li, Jingxia, Wu, Xue-Ru, Huang, Chuanshu
Publicado 2016

Molecular networks discriminating mouse bladder responses to intravesical bacillus Calmette-Guerin (BCG), LPS, and TNF-α

por Saban, Marcia R, O'Donnell, Michael A, Hurst, Robert E, Wu, Xue-Ru, Simpson, Cindy, Dozmorov, Igor, Davis, Carole, Saban, Ricardo
Publicado 2008

E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity

por Liu, Jinyi, Zhang, Dongyun, Luo, Wenjing, Yu, Jianxiu, Li, Jingxia, Yu, Yonghui, Zhang, Xinhai, Chen, Jingyuan, Wu, Xue-Ru, Huang, Chuanshu
Publicado 2012

MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion

por Huang, Chao, Liao, Xin, Jin, Honglei, Xie, Fei, Zheng, Fuxing, Li, Jingxia, Zhou, Chenfan, Jiang, Guosong, Wu, Xue-Ru, Huang, Chuanshu
Publicado 2019

Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS

por Yee, Christopher H., Zheng, Zongyu, Shuman, Lauren, Yamashita, Hironobu, Warrick, Joshua I., Wu, Xue-Ru, Raman, Jay D., DeGraff, David J.
Publicado 2019

The role of TAp63γ and P53 point mutations in regulating DNA repair, mutational susceptibility and invasion of bladder cancer cells

por Wang, Hsiang-Tsui, Lee, Hyun-Wook, Weng, Mao-wen, Liu, Yan, Huang, William C, Lepor, Herbert, Wu, Xue-Ru, Tang, Moon-shong
Publicado 2021

Cellular basis of urothelial squamous metaplasia: roles of lineage heterogeneity and cell replacement

por Liang, Feng-Xia, Bosland, Maarten C., Huang, Hongying, Romih, Rok, Baptiste, Solange, Deng, Fang-Ming, Wu, Xue-Ru, Shapiro, Ellen, Sun, Tung-Tien
Publicado 2005