Photoreceptor metabolic reprogramming: current understanding and therapeutic implications

por Pan, Warren W., Wubben, Thomas J., Besirli, Cagri G.
Publicado 2021

Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration

por Wubben, Thomas J., Pawar, Mercy, Smith, Andrew, Toolan, Kevin, Hager, Heather, Besirli, Cagri G.
Publicado 2017

Presbyopia: a pilot investigation of the barriers and benefits of near visual acuity correction among a rural Filipino population

por Wubben, Thomas J, Guerrero, Christopher M, Salum, Marlo, Wolfe, Gregory S, Giovannelli, Gerald P, Ramsey, David J
Publicado 2014

Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress

por Weh, Eric, Lutrzykowska, Zuzanna, Smith, Andrew, Hager, Heather, Pawar, Mercy, Wubben, Thomas J., Besirli, Cagri G.
Publicado 2020

Retinal Detachment After Endophthalmitis: Risk Factors and Outcomes

por Wang, Tiantian, Moinuddin, Omar, Abuzaitoun, Rebhi, Hwang, Min, Besirli, Cagri, Wubben, Thomas J, Zacks, David N
Publicado 2021

Contemporary Management of Complex and Non-Complex Rhegmatogenous Retinal Detachment Due to Giant Retinal Tears

por Li, Katie X, Carducci, Nicholas, Moinuddin, Omar, Zhou, Yunshu, Musch, David C, Zacks, David N, Besirli, Cagri G, Wubben, Thomas J
Publicado 2021

Metabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration

por Weh, Eric, Goswami, Moloy, Chaudhury, Sraboni, Fernando, Roshini, Miller, Nick, Hager, Heather, Sheskey, Sarah, Sharma, Vikram, Wubben, Thomas J., Besirli, Cagri G.
Publicado 2023

Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis

por Wubben, Thomas J., Chaudhury, Sraboni, Watch, Brennan T., Stuckey, Jeanne A., Weh, Eric, Fernando, Roshini, Goswami, Moloy, Pawar, Mercy, Rech, Jason C., Besirli, Cagri G.
Publicado 2023

Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis

por Wubben, Thomas J., Pawar, Mercy, Weh, Eric, Smith, Andrew, Sajjakulnukit, Peter, Zhang, Li, Dai, Lipeng, Hager, Heather, Pai, Manjunath P., Lyssiotis, Costas A., Besirli, Cagri G.
Publicado 2020

Surgical repair of primary non-complex rhegmatogenous retinal detachment in the modern era of small-gauge vitrectomy

por Moinuddin, Omar, Abuzaitoun, Rebhi O, Hwang, Min W, Sathrasala, Sanjana K, Chen, Xing D, Stein, Joshua D, Johnson, Mark W, Zacks, David N, Wubben, Thomas J, Besirli, Cagri G
Publicado 2021

A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells

por Kamat, Varun, Grumbine, Matthew K., Bao, Khang, Mokate, Kedar, Khalil, Gamal, Cook, Daniel, Clearwater, Brandon, Hirst, Richard, Harman, Jarrod, Boeck, Myriam, Fu, Zhongjie, Smith, Lois E.H., Goswami, Moloy, Wubben, Thomas J., Walker, Emily M., Zhu, Jie, Soleimanpour, Scott A., Scarlett, Jarrad M., Robbings, Brian M., Hass, Daniel, Hurley, James B., Sweet, Ian R.
Publicado 2023