Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

por Grunt, Thomas W., Slany, Astrid, Semkova, Mariya, Colomer, Ramón, López-Rodríguez, María Luz, Wuczkowski, Michael, Wagner, Renate, Gerner, Christopher, Stübiger, Gerald
Publicado 2020

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

por Wagner, Renate, Stübiger, Gerald, Veigel, Daniel, Wuczkowski, Michael, Lanzerstorfer, Peter, Weghuber, Julian, Karteris, Emmanouil, Nowikovsky, Karin, Wilfinger-Lutz, Nastasia, Singer, Christian F., Colomer, Ramón, Benhamú, Bellinda, López-Rodríguez, María Luz, Valent, Peter, Grunt, Thomas W.
Publicado 2017