The amplifier effect: how Pin1 empowers mutant p53

por Hu, Hai, Wulf, Gerburg M
Publicado 2011

Closing escape routes: inhibition of IL-8 signaling enhances the anti-tumor efficacy of PI3K inhibitors

por Juvekar, Ashish, Wulf, Gerburg M
Publicado 2013

Serial-omics of P53−/−, Brca1−/− Mouse Breast Tumor and Normal Mammary Gland

por Breitkopf, Susanne B., Taveira, Mateus De Oliveira, Yuan, Min, Wulf, Gerburg M., Asara, John M.
Publicado 2017

An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

por Przybytkowski, Ewa, Davis, Thomas, Hosny, Abdelrahman, Eismann, Julia, Matulonis, Ursula A., Wulf, Gerburg M., Nabavi, Sheida
Publicado 2020

Response of Brain Metastases From PIK3CA-Mutant Breast Cancer to Alpelisib

por Batalini, Felipe, Moulder, Stacy L., Winer, Eric P., Rugo, Hope S., Lin, Nancy U., Wulf, Gerburg M.
Publicado 2020

STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer

por Pantelidou, Constantia, Jadhav, Heta, Kothari, Aditi, Liu, Renyan, Wulf, Gerburg M., Guerriero, Jennifer L., Shapiro, Geoffrey I.
Publicado 2022

Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

por Lam, Prudence B, Burga, Laura N, Wu, Bryan P, Hofstatter, Erin W, Lu, Kun Ping, Wulf, Gerburg M
Publicado 2008

Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen rec...

por Burga, Laura N, Hu, Hai, Juvekar, Ashish, Tung, Nadine M, Troyan, Susan L, Hofstatter, Erin W, Wulf, Gerburg M
Publicado 2011

Genomic characteristics of trastuzumab-resistant Her2-positive metastatic breast cancer

por de Oliveira Taveira, Mateus, Nabavi, Sheida, Wang, Yuker, Tonellato, Peter, Esteva, Francisco J., Cantley, Lewis C., Wulf, Gerburg M.
Publicado 2017

Invasive Ductal Carcinoma of the Breast in a Transgender Man: A Case Report

por Heng, Yujing J., Zhang, Kevin J., Valero, Monica G., Baker, Gabrielle M., Fein-Zachary, Valerie J., Irwig, Michael S., Wulf, Gerburg M.
Publicado 2023

Phosphoinositide 3-Kinase regulates glycolysis through mobilization of Aldolase A from the actin cytoskeleton

por Hu, Hai, Juvekar, Ashish, Lyssiotis, Costas, Albeck, John G, Tolan, Dean R, Asara, John M, Wulf, Gerburg M, Cantley, Lewis C
Publicado 2014

Blockade of 6-phosphogluconate dehydrogenase generates CD8(+) effector T cells with enhanced anti-tumor function

por Daneshmandi, Saeed, Cassel, Teresa, Lin, Penghui, Higashi, Richard M., Wulf, Gerburg M., Boussiotis, Vassiliki A., Fan, Teresa W.-M., Seth, Pankaj
Publicado 2021

Establishing a Cohort of Transgender Men and Gender Nonconforming Individuals to Understand the Molecular Impact of Testosterone on Breast Physiology

por Baker, Gabrielle M., Pyle, Michael E., Tobias, Adam M., Bartlett, Richard A., Phillips, Jordana, Fein-Zachary, Valerie J., Wulf, Gerburg M., Heng, Yujing J.
Publicado 2019

Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib

por Eismann, Julia, Heng, Yujing J., Waldschmidt, Johannes M., Vlachos, Ioannis S., Gray, Kathryn P., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A., Murphy, Charles J., Nabavi, Sheida, Wulf, Gerburg M.
Publicado 2019

Homologous Recombination Deficiency Landscape of Breast Cancers and Real-World Effectiveness of Poly ADP-Ribose Polymerase Inhibitors in Patients With Somatic BRCA1/2, Germline PAL...

por Batalini, Felipe, Madison, Russell W., Sokol, Ethan S., Jin, Dexter X., Chen, Kuei-Ting, Decker, Brennan, Pavlick, Dean C., Frampton, Garrett M., Wulf, Gerburg M., Garber, Judy E., Oxnard, Geoffrey, Schrock, Alexa B., Tung, Nadine M.
Publicado 2023

Epstein–Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation()

por Hu, Hai, Luo, Man-Li, Desmedt, Christine, Nabavi, Sheida, Yadegarynia, Sina, Hong, Alex, Konstantinopoulos, Panagiotis A., Gabrielson, Edward, Hines-Boykin, Rebecca, Pihan, German, Yuan, Xin, Sotirious, Christos, Dittmer, Dirk P., Fingeroth, Joyce D., Wulf, Gerburg M.
Publicado 2016

Testosterone therapy and breast histopathological features in transgender individuals

por Baker, Gabrielle M, Guzman-Arocho, Yaileen D, Bret-Mounet, Vanessa C, Torous, Vanda F, Schnitt, Stuart J, Tobias, Adam M, Bartlett, Richard A, Fein-Zachary, Valerie J, Collins, Laura C, Wulf, Gerburg M, Heng, Yujing J
Publicado 2020

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

por Patterson-Fortin, Jeffrey, Jadhav, Heta, Pantelidou, Constantia, Phan, Tin, Grochala, Carter, Mehta, Anita K., Guerriero, Jennifer L., Wulf, Gerburg M., Wolpin, Brian M., Stanger, Ben Z., Aguirre, Andrew J., Cleary, James M., D’Andrea, Alan D., Shapiro, Geoffrey I.
Publicado 2023

Rac1 activates non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer

por Li, Qingjian, Qin, Tao, Bi, Zhuofei, Hong, Huangming, Ding, Lin, Chen, Jiewen, Wu, Wei, Lin, Xiaorong, Fu, Wenkui, Zheng, Fang, Yao, Yandan, Luo, Man-Li, Saw, Phei Er, Wulf, Gerburg M., Xu, Xiaoding, Song, Erwei, Yao, Herui, Hu, Hai
Publicado 2020

Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer

por Waks, Adrienne G, Keenan, Tanya E, Li, Tianyu, Tayob, Nabihah, Wulf, Gerburg M, Richardson, Edward T, Attaya, Victoria, Anderson, Leilani, Mittendorf, Elizabeth A, Overmoyer, Beth, Winer, Eric P, Krop, Ian E, Agudo, Judith, Van Allen, Eliezer M, Tolaney, Sara M
Publicado 2022