Pharmacological characterization of receptor guanylyl cyclase reporter cell lines

por Wunder, Frank, Barufe, Daniel, Woermann, Annette, Milde, Markus
Publicado 2009

A Multidimensional Strategy to Detect Polypharmacological Targets in the Absence of Structural and Sequence Homology

por Durrant, Jacob D., Amaro, Rommie E., Xie, Lei, Urbaniak, Michael D., Ferguson, Michael A. J., Haapalainen, Antti, Chen, Zhijun, Di Guilmi, Anne Marie, Wunder, Frank, Bourne, Philip E., McCammon, J. Andrew
Publicado 2010

BAY-6096: A Potent, Selective, and Highly Water-Soluble Adrenergic α(2B) Antagonist

por Meibom, Daniel, Meyer, Jutta, von Buehler, Clemens-Jeremias, Collins, Karl D., Maassen, Stefanie, Gericke, Kersten Matthias, Hüser, Jörg, Mittendorf, Joachim, Ortega Hernandez, Nuria, Schamberger, Jens, Stampfuss, Jan, Straub, Alexander, Torge, Afra, Witowski, Norbert, Wunder, Frank
Publicado 2023

Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension

por Mittendorf, Joachim, Weigand, Stefan, Alonso-Alija, Cristina, Bischoff, Erwin, Feurer, Achim, Gerisch, Michael, Kern, Armin, Knorr, Andreas, Lang, Dieter, Muenter, Klaus, Radtke, Martin, Schirok, Hartmut, Schlemmer, Karl-Heinz, Stahl, Elke, Straub, Alexander, Wunder, Frank, Stasch, Johannes-Peter
Publicado 2009

Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption...

por Egbert, Jeremy R., Uliasz, Tracy F., Shuhaibar, Leia C., Geerts, Andreas, Wunder, Frank, Kleiman, Robin J., Humphrey, John M., Lampe, Paul D., Artemyev, Nikolai O., Rybalkin, Sergei D., Beavo, Joseph A., Movsesian, Matthew A., Jaffe, Laurinda A.
Publicado 2016

BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor

por Meibom, Daniel, Micus, Sina, Andreevski, Anna Lena, Anlauf, Sonja, Bogner, Pamela, von Buehler, Clemens-Jeremias, Dieskau, André P., Dreher, Jan, Eitner, Frank, Fliegner, Daniela, Follmann, Markus, Gericke, Kersten Matthias, Maassen, Stefanie, Meyer, Jutta, Schlemmer, Karl-Heinz, Steuber, Holger, Tersteegen, Adrian, Wunder, Frank
Publicado 2022

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation

por Mauersberger, Carina, Sager, Hendrik B., Wobst, Jana, Dang, Tan An, Lambrecht, Laura, Koplev, Simon, Stroth, Marlène, Bettaga, Noomen, Schlossmann, Jens, Wunder, Frank, Friebe, Andreas, Björkegren, Johan L. M., Dietz, Lisa, Maas, Sanne L., van der Vorst, Emiel P. C., Sandner, Peter, Soehnlein, Oliver, Schunkert, Heribert, Kessler, Thorsten
Publicado 2022

Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC

por Becker-Pelster, Eva M., Hahn, Michael G., Delbeck, Martina, Dietz, Lisa, Hüser, Jörg, Kopf, Johannes, Kraemer, Thomas, Marquardt, Tobias, Mondritzki, Thomas, Nagelschmitz, Johannes, Nikkho, Sylvia M., Pires, Philippe V., Tinel, Hanna, Weimann, Gerrit, Wunder, Frank, Sandner, Peter, Schuhmacher, Joachim, Stasch, Johannes-Peter, Truebel, Hubert K. F.
Publicado 2022