CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies

por Knochelmann, Hannah M., Smith, Aubrey S., Dwyer, Connor J., Wyatt, Megan M., Mehrotra, Shikhar, Paulos, Chrystal M.
Publicado 2018

The Basics of Artificial Antigen Presenting Cells in T Cell-Based Cancer Immunotherapies

por Neal, Lillian R., Bailey, Stefanie R., Wyatt, Megan M., Bowers, Jacob S., Majchrzak, Kinga, Nelson, Michelle H., Haupt, Carl, Paulos, Chrystal M., Varela, Juan C.
Publicado 2017

Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy

por Rangel Rivera, Guillermo O., Knochelmann, Hannah M., Dwyer, Connor J., Smith, Aubrey S., Wyatt, Megan M., Rivera-Reyes, Amalia M., Thaxton, Jessica E., Paulos, Chrystal M.
Publicado 2021

PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8(+) T Cells

por Bowers, Jacob S., Majchrzak, Kinga, Nelson, Michelle H., Aksoy, Bulent Arman, Wyatt, Megan M., Smith, Aubrey S., Bailey, Stefanie R., Neal, Lillian R., Hammerbacher, Jeffrey E., Paulos, Chrystal M.
Publicado 2017

Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines

por Dwyer, Connor J., Knochelmann, Hannah M., Smith, Aubrey S., Wyatt, Megan M., Rangel Rivera, Guillermo O., Arhontoulis, Dimitrios C., Bartee, Eric, Li, Zihai, Rubinstein, Mark P., Paulos, Chrystal M.
Publicado 2019

Human CD26(high) T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence

por Bailey, Stefanie R., Nelson, Michelle H., Majchrzak, Kinga, Bowers, Jacob S., Wyatt, Megan M., Smith, Aubrey S., Neal, Lillian R., Shirai, Keisuke, Carpenito, Carmine, June, Carl H., Zilliox, Michael J., Paulos, Chrystal M.
Publicado 2017

Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8(+) T cells

por Dwyer, Connor J., Arhontoulis, Dimitrios C., Rangel Rivera, Guillermo O, Knochelmann, Hannah M., Smith, Aubrey S., Wyatt, Megan M., Rubinstein, Mark P., Atkinson, Carl, Thaxton, Jessica E., Neskey, David M., Paulos, Chrystal M.
Publicado 2020

B cells imprint adoptively transferred CD8(+) T cells with enhanced tumor immunity

por Smith, Aubrey S, Knochelmann, Hannah M, Wyatt, Megan M, Rangel Rivera, Guillermo O, Rivera-Reyes, Amalia M, Dwyer, Connor J, Ware, Michael B, Cole, Anna C, Neskey, David M, Rubinstein, Mark P, Liu, Bei, Thaxton, Jessica E, Bartee, Eric, Paulos, Chrystal M
Publicado 2022

Identification of human CD4(+) T cell populations with distinct antitumor activity

por Nelson, Michelle H., Knochelmann, Hannah M., Bailey, Stefanie R., Huff, Logan W., Bowers, Jacob S., Majchrzak-Kuligowska, Kinga, Wyatt, Megan M., Rubinstein, Mark P., Mehrotra, Shikhar, Nishimura, Michael I., Armeson, Kent E., Giresi, Paul G., Zilliox, Michael J., Broxmeyer, Hal E., Paulos, Chrystal M.
Publicado 2020

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

por Knochelmann, Hannah M, Rivera-Reyes, Amalia M, Wyatt, Megan M, Smith, Aubrey S, Chamness, Reilley, Dwyer, Connor J, Bobian, Michael, Rangel Rivera, Guillermo O, Horton, Joshuva D, Lilly, Michael, Romeo, Martin J, Timmers, Cynthia D, Rubinstein, Mark P, Neskey, David M, Paulos, Chrystal M
Publicado 2021

Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma

por Knochelmann, Hannah M., Horton, Joshua D., Liu, Sixue, Armeson, Kent, Kaczmar, John M., Wyatt, Megan M., Richardson, Mary S., Lomeli, Shirley H., Xiong, Ying, Graboyes, Evan M., Lentsch, Eric J., Hornig, Joshua D., Skoner, Judith, Stalcup, Seth, Spampinato, Maria V., Garrett-Mayer, Elizabeth, O’Quinn, Elizabeth C., Timmers, Cynthia D., Romeo, Martin J., Wrangle, John M., Young, M. Rita I., Rubinstein, Mark P., Day, Terry A., Lo, Roger S., Paulos, Chrystal M., Neskey, David M.
Publicado 2021