Contribution of NMDA Receptors to Synaptic Function in Rat Hippocampal Interneurons

por Booker, Sam A., Sumera, Anna, Kind, Peter C., Wyllie, David J. A.
Publicado 2021

Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells

por Livesey, Matthew R., Magnani, Dario, Hardingham, Giles E., Chandran, Siddharthan, Wyllie, David J. A.
Publicado 2015

Functional assessment of the NMDA receptor variant GluN2A (R586K)

por Marwick, Katie F.M., Parker, Peter, Skehel, Paul, Hardingham, Giles, Wyllie, David J.A.
Publicado 2017

The human NMDA receptor GluN2A(N615K) variant influences channel blocker potency

por Marwick, Katie F. M., Skehel, Paul A., Hardingham, Giles E., Wyllie, David J. A.
Publicado 2019

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg(2+) and memantine under conditions of agonist exposure

por McKay, Sean, Bengtson, C. Peter, Bading, Hilmar, Wyllie, David J.A., Hardingham, Giles E.
Publicado 2013

Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy

por Marwick, Katie F. M., Hansen, Kasper B., Skehel, Paul A., Hardingham, Giles E., Wyllie, David J. A.
Publicado 2019

Cellular and synaptic phenotypes lead to disrupted information processing in Fmr1-KO mouse layer 4 barrel cortex

por Domanski, Aleksander P. F., Booker, Sam A., Wyllie, David J. A., Isaac, John T. R., Kind, Peter C.
Publicado 2019

Activin/Nodal Inhibition Alone Accelerates Highly Efficient Neural Conversion from Human Embryonic Stem Cells and Imposes a Caudal Positional Identity

por Patani, Rickie, Compston, Alastair, Puddifoot, Clare A., Wyllie, David J. A., Hardingham, Giles E., Allen, Nicholas D., Chandran, Siddharthan
Publicado 2009

Reduced local input to fast‐spiking interneurons in the somatosensory cortex in the GABA(A) γ2 R43Q mouse model of absence epilepsy

por Currie, Stephen P., Luz, Liliana L., Booker, Sam A., Wyllie, David J. A., Kind, Peter C., Daw, Michael I.
Publicado 2017

Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

por Booker, Sam A., Campbell, Graham R., Mysiak, Karolina S., Brophy, Peter J., Kind, Peter C., Mahad, Don J., Wyllie, David J. A.
Publicado 2017

Physiological Normoxia and Absence of EGF Is Required for the Long-Term Propagation of Anterior Neural Precursors from Human Pluripotent Cells

por Bilican, Bilada, Livesey, Matthew R., Haghi, Ghazal, Qiu, Jing, Burr, Karen, Siller, Rick, Hardingham, Giles E., Wyllie, David J. A., Chandran, Siddharthan
Publicado 2014

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals

por Qiu, Jing, Tan, Yan-Wei, Hagenston, Anna M., Martel, Marc-Andre, Kneisel, Niclas, Skehel, Paul A., Wyllie, David J. A., Bading, Hilmar, Hardingham, Giles E.
Publicado 2013

Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition

por Rzechorzek, Nina M., Connick, Peter, Livesey, Matthew R., Borooah, Shyamanga, Patani, Rickie, Burr, Karen, Story, David, Wyllie, David J.A., Hardingham, Giles E., Chandran, Siddharthan
Publicado 2015

Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST

por Perkins, Emma M., Suminaite, Daumante, Clarkson, Yvonne L., Lee, Sin Kwan, Lyndon, Alastair R., Rothstein, Jeffrey D., Wyllie, David J.A., Tanaka, Kohichi, Jackson, Mandy
Publicado 2016

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells

por Perkins, Emma M, Clarkson, Yvonne L, Suminaite, Daumante, Lyndon, Alastair R, Tanaka, Kohichi, Rothstein, Jeffrey D, Skehel, Paul A, Wyllie, David J A, Jackson, Mandy
Publicado 2018

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

por Booker, Sam A., Domanski, Aleksander P. F., Dando, Owen R., Jackson, Adam D., Isaac, John T. R., Hardingham, Giles E., Wyllie, David J. A., Kind, Peter C.
Publicado 2019

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

por Sharma, Shreya Das, Reddy, Bharath Kumar, Pal, Rakhi, Ritakari, Tuula E., Cooper, James D., Selvaraj, Bhuvaneish T., Kind, Peter C., Chandran, Siddharthan, Wyllie, David J.A., Chattarji, Sumantra
Publicado 2023

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

por Patani, Rickie, Lewis, Patrick A, Trabzuni, Daniah, Puddifoot, Clare A, Wyllie, David J A, Walker, Robert, Smith, Colin, Hardingham, Giles E, Weale, Michael, Hardy, John, Chandran, Siddharthan, Ryten, Mina
Publicado 2012

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

por James, Owain T, Livesey, Matthew R, Qiu, Jing, Dando, Owen, Bilican, Bilada, Haghi, Ghazal, Rajan, Rinku, Burr, Karen, Hardingham, Giles E, Chandran, Siddharthan, Kind, Peter C, Wyllie, David J A
Publicado 2014

Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome

por Thomson, Sophie R., Seo, Sang S., Barnes, Stephanie A., Louros, Susana R., Muscas, Melania, Dando, Owen, Kirby, Caoimhe, Wyllie, David J.A., Hardingham, Giles E., Kind, Peter C., Osterweil, Emily K.
Publicado 2017