A Novel Pool of Microparticle Cholesterol Is Elevated in Rheumatoid Arthritis but Not in Systemic Lupus Erythematosus Patients

por Hu, Shuaishuai, Cavanagh, Brenton L., Harrington, Robert, Ahmad, Muddassar, Kearns, Grainne, Meaney, Steve, Wynne, Claire
Publicado 2020

Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

por Shahnazaryan, David, Khalil, Rana, Wynne, Claire, Jefferies, Caroline A., Ní Gabhann-Dromgoole, Joan, Murphy, Conor C.
Publicado 2020

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors

por Higgs, Rowan, Lazzari, Elisa, Wynne, Claire, Ní Gabhann, Joan, Espinosa, Alexander, Wahren-Herlenius, Marie, Jefferies, Caroline A.
Publicado 2010

Genetics of SLE: Functional Relevance for Monocytes/Macrophages in Disease

por Byrne, Jennifer C., Ní Gabhann, Joan, Lazzari, Elisa, Mahony, Rebecca, Smith, Siobhán, Stacey, Kevin, Wynne, Claire, Jefferies, Caroline A.
Publicado 2012

Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide

por Ní Gabhann, Joan, Hams, Emily, Smith, Siobhán, Wynne, Claire, Byrne, Jennifer C., Brennan, Kiva, Spence, Shaun, Kissenpfennig, Adrien, Johnston, James A., Fallon, Padraic G., Jefferies, Caroline A.
Publicado 2014

TRIM68 Negatively Regulates IFN-β Production by Degrading TRK Fused Gene, a Novel Driver of IFN-β Downstream of Anti-Viral Detection Systems

por Wynne, Claire, Lazzari, Elisa, Smith, Siobhán, McCarthy, Eoghan M., Ní Gabhann, Joan, Kallal, Lara E., Higgs, Rowan, Cryan, Sally Ann, Biron, Christine A., Jefferies, Caroline A.
Publicado 2014

TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages

por Li, Yang, James, Sharmy J., Wyllie, David H., Wynne, Claire, Czibula, Agnes, Bukhari, Ahmed, Pye, Katherine, Bte Mustafah, Seri Musfirah, Fajka-Boja, Roberta, Szabo, Eniko, Angyal, Adrienn, Hegedus, Zoltan, Kovacs, Laszlo, Hill, Adrian V. S., Jefferies, Caroline A., Wilson, Heather L., Yongliang, Zhang, Kiss-Toth, Endre
Publicado 2019