Engineered Maturation Approaches of Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes

por Ge, Feixiang, Wang, Zetian, Xi, Jianzhong Jeff
Publicado 2019

CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

por Luo, Yufeng, Ge, Mei, Wang, Bolun, Sun, Changhong, Wang, Junyi, Dong, Yuyang, Xi, Jianzhong Jeff
Publicado 2020

A Magnetic Bead-Integrated Chip for the Large Scale Manufacture of Normalized esiRNAs

por Wang, Zhao, Huang, Huang, Zhang, Hanshuo, Sun, Changhong, Hao, Yang, Yang, Junyu, Fan, Yu, Xi, Jianzhong Jeff
Publicado 2012

The synergistic regulation of VEGF-mediated angiogenesis through miR-190 and target genes

por Hao, Yang, Yang, Junyu, Yin, Shenyi, Zhang, Hanshuo, Fan, Yu, Sun, Changhong, Gu, Jin, Xi, Jianzhong Jeff
Publicado 2014

Efficient generation of mice carrying homozygous double-floxp alleles using the Cas9-Avidin/Biotin-donor DNA system

por Ma, Ming, Zhuang, Fengfeng, Hu, Xiongbing, Wang, Bolun, Wen, Xian-Zi, Ji, Jia-Fu, Xi, Jianzhong Jeff
Publicado 2017

Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos

por Chang, Nannan, Sun, Changhong, Gao, Lu, Zhu, Dan, Xu, Xiufei, Zhu, Xiaojun, Xiong, Jing-Wei, Xi, Jianzhong Jeff
Publicado 2013

miR-19b promotes tumor growth and metastasis via targeting TP53

por Fan, Yu, Yin, Shenyi, Hao, Yang, Yang, Junyu, Zhang, Hanshuo, Sun, Changhong, Ma, Ming, Chang, Qing, Xi, Jianzhong Jeff
Publicado 2014

High-throughput saturation mutagenesis generates a high-affinity antibody against SARS-CoV-2 variants using protein surface display assay on a human cell

por Yang, Ye, Liu, Shuo, Luo, Yufeng, Wang, Bolun, Wang, Junyi, Li, Juan, Li, Jiaxin, Ye, Buqing, Wang, Youchun, Xi, Jianzhong Jeff
Publicado 2023

Engineered TAL Effector modulators for the large-scale gain-of-function screening

por Zhang, Hanshuo, Li, Juan, Hou, Sha, Wang, Gancheng, Jiang, Mingjun, Sun, Changhong, Hu, Xiongbing, Zhuang, Fengfeng, Dai, Zhifei, Dai, Junbiao, Xi, Jianzhong Jeff
Publicado 2014

Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs

por Yao, Jing, Huang, Jiaojiao, Hai, Tang, Wang, Xianlong, Qin, Guosong, Zhang, Hongyong, Wu, Rong, Cao, Chunwei, Xi, Jianzhong Jeff, Yuan, Zengqiang, Zhao, Jianguo
Publicado 2014

Suppression of SHROOM1 Improves In Vitro and In Vivo Gene Integration by Promoting Homology-Directed Repair

por Zhao, Zhihua, Zhang, Hanshuo, Xiong, Tuanlin, Wang, Junyi, Yang, Di, Zhu, Dan, Li, Juan, Yang, Ye, Sun, Changhong, Zhao, Yuting, Xi, Jianzhong Jeff
Publicado 2020

Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion

por Zhang, Yuying, Guo, Anqi, Lyu, Cheng, Bi, Ran, Wu, Zhaozhao, Li, Wenjing, Zhao, Peng, Niu, Yudi, Na, Jie, Xi, Jianzhong Jeff, Du, Yanan
Publicado 2021

Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis

por Yin, Shenyi, Fan, Yu, Zhang, Hanshuo, Zhao, Zhihua, Hao, Yang, Li, Juan, Sun, Changhong, Yang, Junyu, Yang, Zhenjun, Yang, Xiao, Lu, Jian, Xi, Jianzhong Jeff
Publicado 2016

B7H3-targeting chimeric antigen receptor modification enhances antitumor effect of Vγ9Vδ2 T cells in glioblastoma

por Wang, Yi, Ji, Nan, Zhang, Yang, Chu, Junsheng, Pan, Changcun, Zhang, Peng, Ma, Weiwei, Zhang, Xueguang, Xi, Jianzhong Jeff, Chen, Mingze, Zhang, Yonghui, Zhang, Liwei, Sun, Tao
Publicado 2023

ACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants

por Wang, Bolun, Zhao, Junxuan, Liu, Shuo, Feng, Jingyuan, Luo, Yufeng, He, Xinyu, Wang, Yanmin, Ge, Feixiang, Wang, Junyi, Ye, Buqing, Huang, Weijin, Bo, Xiaochen, Wang, Youchun, Xi, Jianzhong Jeff
Publicado 2022

High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2

por Luo, Yufeng, Liu, Shuo, Xue, Jiguo, Yang, Ye, Zhao, Junxuan, Sun, Ying, Wang, Bolun, Yin, Shenyi, Li, Juan, Xia, Yuchao, Ge, Feixiang, Dong, Jiqiao, Guo, Lvze, Ye, Buqing, Huang, Weijin, Wang, Youchun, Xi, Jianzhong Jeff
Publicado 2023