Predicting Approximate Clinically Effective Doses in Oncology Using Preclinical Efficacy and Body Surface Area Conversion: A Retrospective Analysis

por Griffin, Robert J., Avery, Ethan, Xia, Cindy Q.
Publicado 2022

Development of minimal physiologically-based pharmacokinetic-pharmacodynamic models for characterizing cellular kinetics of CAR T cells following local deliveries in mice

por Tsai, Chia-Hung, Singh, Aman P., Xia, Cindy Q., Wang, Haiqing
Publicado 2022

The Perspective of DMPK on Recombinant Adeno-Associated Virus-Based Gene Therapy: Past Learning, Current Support, and Future Contribution

por Chen, Nancy, Sun, Kefeng, Chemuturi, Nagendra Venkata, Cho, Hyelim, Xia, Cindy Q.
Publicado 2022

Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development

por Lai, Yurong, Chu, Xiaoyan, Di, Li, Gao, Wei, Guo, Yingying, Liu, Xingrong, Lu, Chuang, Mao, Jialin, Shen, Hong, Tang, Huaping, Xia, Cindy Q., Zhang, Lei, Ding, Xinxin
Publicado 2022

Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper

por Yang, Tong-yuan, Braun, Manuela, Lembke, Wibke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Chandode, Rakesh Kantilal, Stubenrauch, Kay-Gunnar, Vinzing, Maya, Xia, Cindy Q., Jawa, Vibha
Publicado 2022