The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies

por Senter, Rebecca K., Ghoshal, Ayan, Walker, Adam G., Xiang, Zixiu, Niswender, Colleen M., Conn, P. Jeffrey
Publicado 2016

Ultrasound neuromodulation depends on pulse repetition frequency and can modulate inhibitory effects of TTX

por Manuel, Thomas J., Kusunose, Jiro, Zhan, Xiaoyan, Lv, Xiaohui, Kang, Ellison, Yang, Aaron, Xiang, Zixiu, Caskey, Charles F.
Publicado 2020

mGlu(5) Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu(5)-Endocannabinoid Signaling

por Xiang, Zixiu, Lv, Xiaohui, Maksymetz, James, Stansley, Branden J., Ghoshal, Ayan, Gogliotti, Rocco G., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey
Publicado 2019

Differential activity of mGlu(7) allosteric modulators provides evidence for mGlu(7/8) heterodimers at hippocampal Schaffer collateral-CA1 synapses

por Lin, Xin, Fisher, Nicole M., Dogra, Shalini, Senter, Rebecca K., Reed, Carson W., Kalbfleisch, Jacob J., Lindsley, Craig W., Asher, Wesley B., Xiang, Zixiu, Niswender, Colleen M., Javitch, Jonathan A.
Publicado 2022

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning

por Ayala, Jennifer E., Chen, Yelin, Banko, Jessica L., Sheffler, Douglas J., Williams, Richard, Telk, Alexandra N., Watson, Noreen L., Xiang, Zixiu, Zhang, Yongqin, Jones, Paulianda J., Lindsley, Craig W., Olive, M. Foster, Conn, P. Jeffrey
Publicado 2009

Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7

por Jalan-Sakrikar, Nidhi, Field, Julie R., Klar, Rebecca, Mattmann, Margrith E., Gregory, Karen J., Zamorano, Rocio, Engers, Darren W., Bollinger, Sean R., Weaver, C. David, Days, Emily L., Lewis, L. Michelle, Utley, Thomas J., Hurtado, Miguel, Rigault, Delphine, Acher, Francine, Walker, Adam G., Melancon, Bruce J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Xiang, Zixiu, Hopkins, Corey R., Niswender, Colleen M.
Publicado 2014